Bioorthogonal chemistry: Optimization and application updates during 2013-2017
文献类型：期刊论文
| 作者 | Qin, Li-Huai1,2,3; Hu, Wei1; Long, Ya-Qiu1 |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2018-06-06 |
| 卷号 | 59期号:23页码:2214-2228 |
| 关键词 | Bioorthogonal reaction Ligation Decaging Fluorescent probes |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2018.04.058 |
| 文献子类 | Review |
| 英文摘要 | Bioorthogonal chemical groups to tag naturally occurring biomolecules in their native setting is a powerful tool for studying and manipulating biological processes, whereby unique functional groups incorporated into target biomolecules can be detected in a second step by using selective partners. On the other hand, bioorthogonal cleavage reactions enables chemically controlled spatiotemporal activation of intracellular proteins and prodrugs. Considerable attention has been focused on the bioorthogonal reactions, not only optimizing the known bioorthogonal reagents to gain fast reaction kinetics, high stability of the reagents and the products, but also extending new applications as well as developing new types of bioorthogonal reactions. (C) 2018 Elsevier Ltd. All rights reserved. |
| WOS关键词 | AZIDE-ALKYNE CYCLOADDITION ; DIELS-ALDER REACTIONS ; AQUEOUS-SOLUTION ; INTRACELLULAR PROTEINS ; TETRAZINE DERIVATIVES ; TRANS-CYCLOOCTENE ; AMINO-ACIDS ; NEUTRAL PH ; CLICK ; LIGATION |
| 资助项目 | National Natural Science Foundation of China[81325020] ; National Natural Science Foundation of China[21772214] ; National Natural Science Foundation of China[81761128022] ; Shanghai Municipal Committee of Science and Technology[15431901400] ; Shanghai Municipal Committee of Science and Technology[16431901900] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000446641000003 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279713]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Long, Ya-Qiu |
| 作者单位 | 1.Soochow Univ, Coll Pharmaceut Sci, Lab Med Chem Biol, Med Coll, 199 Renai Rd, Suzhou 215123, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China; 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qin, Li-Huai,Hu, Wei,Long, Ya-Qiu. Bioorthogonal chemistry: Optimization and application updates during 2013-2017[J]. TETRAHEDRON LETTERS,2018,59(23):2214-2228. |
| APA | Qin, Li-Huai,Hu, Wei,&Long, Ya-Qiu.(2018).Bioorthogonal chemistry: Optimization and application updates during 2013-2017.TETRAHEDRON LETTERS,59(23),2214-2228. |
| MLA | Qin, Li-Huai,et al."Bioorthogonal chemistry: Optimization and application updates during 2013-2017".TETRAHEDRON LETTERS 59.23(2018):2214-2228. |
入库方式： OAI收割
来源：上海药物研究所
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