Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens
文献类型：期刊论文
| 作者 | Zhang, Shuaibing2; Huang, Ying1; He, Shijun3 ; Chen, Heping2; Li, Zhenghui2; Wu, Bin2; Zuo, Jianping3; Feng, Tao2; Liu, Jikai2
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2018 |
| 卷号 | 8期号:42页码:23914-23918 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c8ra04226h |
| 文献子类 | Article |
| 英文摘要 | A chemical study of the common species Albatrellus confluens present in Yunnan province, southwest China led to the identification of a pair of epimers named albatredines A (1) and B (2). They feature a natural unprecedented 1,2,4-oxadiazolidin-5-one skeleton. The acyl substitution pattern and complete configurational assignments were deduced from the comparison between experimental and theoretical C-13 NMR and ECD data, respectively. Bioassay results showed that compound 1 exhibited a weak immunosuppressive activity against the concanavalin A-induced T lymphocyte cell proliferation (IC50 2.99 M). |
| WOS关键词 | DERIVATIVES ; ALBACONOL ; CULTURES ; ACID |
| 资助项目 | National Natural Science Foundation of China[81561148013] ; National Natural Science Foundation of China[81373289] ; Key Projects of Technological Innovation of Hubei Province[2016ACA138] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000437475600046 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272308]  |
| 专题 | 药理学第一研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Zuo, Jianping; Feng, Tao; Liu, Jikai |
| 作者单位 | 1.Leibniz Inst Nat Prod Res & Infect Biol HKI, Leibniz Res Grp Biobricks Microbial Nat Prod Synt, Adolf Reichwein Str 23, D-07745 Jena, Germany; 2.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Shuaibing,Huang, Ying,He, Shijun,et al. Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens[J]. RSC ADVANCES,2018,8(42):23914-23918. |
| APA | Zhang, Shuaibing.,Huang, Ying.,He, Shijun.,Chen, Heping.,Li, Zhenghui.,...&Liu, Jikai.(2018).Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens.RSC ADVANCES,8(42),23914-23918. |
| MLA | Zhang, Shuaibing,et al."Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens".RSC ADVANCES 8.42(2018):23914-23918. |
入库方式： OAI收割
来源：上海药物研究所
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