中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review

文献类型:期刊论文

作者Shah, Sayed Asmat Ali2; Akhter, Najeeb2; Auckloo, Bibi Nazia2; Khan, Ishrat2; Lu, Yanbin3; Wang, Kuiwu3; Wu, Bin2; Guo, Yue-Wei1
刊名MARINE DRUGS
出版日期2017-11
卷号15期号:11
关键词cyanobacteria secondary metabolites biological properties and applications
ISSN号1660-3397
DOI10.3390/md15110354
文献子类Review
英文摘要Nowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs followed by an increase in the number of deaths caused by cancer due to chemotherapy resistance as well. Accordingly, marine cyanobacteria, being the oldest prokaryotic microorganisms belonging to a monophyletic group, have proven themselves as being able to generate pharmaceutically important natural products. They have long been known to produce distinct and structurally complex secondary metabolites including peptides, polyketides, alkaloids, lipids, and terpenes with potent biological properties and applications. As such, this review will focus on recently published novel compounds isolated from marine cyanobacteria along with their potential bioactivities such as antibacterial, antifungal, anticancer, anti-tuberculosis, immunosuppressive and anti-inflammatory capacities. Moreover, various structural classes, as well as their technological uses will also be discussed.
WOS关键词SP MARINE CYANOBACTERIUM ; MOOREA-PRODUCENS ; OKEANIA SP ; CYCLIC DEPSIPEPTIDES ; LYNGBYA-MAJUSCULA ; DRUG DISCOVERY ; RED-SEA ; A-D ; CHYMOTRYPSIN INHIBITOR ; SECONDARY METABOLITES
资助项目Natural Science Foundation of China[81573306] ; Natural Science Foundation of China[81520108028] ; SCTSM[15431901000] ; SKLDR/SIMM[SIMM 1705ZZ-01] ; NSF of Zhejiang[LY15C200004]
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000416600200024
出版者MDPI AG
源URL[http://119.78.100.183/handle/2S10ELR8/272418]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Wu, Bin; Guo, Yue-Wei
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
2.Zhejiang Univ, Ocean Coll, Hangzhou 310058, Zhejiang, Peoples R China;
3.Zhejiang Gongshang Univ, Dept Appl Chem, Hangzhou 310012, Zhejiang, Peoples R China;
推荐引用方式
GB/T 7714
Shah, Sayed Asmat Ali,Akhter, Najeeb,Auckloo, Bibi Nazia,et al. Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review[J]. MARINE DRUGS,2017,15(11).
APA Shah, Sayed Asmat Ali.,Akhter, Najeeb.,Auckloo, Bibi Nazia.,Khan, Ishrat.,Lu, Yanbin.,...&Guo, Yue-Wei.(2017).Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review.MARINE DRUGS,15(11).
MLA Shah, Sayed Asmat Ali,et al."Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review".MARINE DRUGS 15.11(2017).

入库方式: OAI收割

来源:上海药物研究所

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