Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review
文献类型:期刊论文
作者 | Shah, Sayed Asmat Ali2; Akhter, Najeeb2; Auckloo, Bibi Nazia2; Khan, Ishrat2; Lu, Yanbin3; Wang, Kuiwu3; Wu, Bin2; Guo, Yue-Wei1![]() |
刊名 | MARINE DRUGS
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出版日期 | 2017-11 |
卷号 | 15期号:11 |
关键词 | cyanobacteria secondary metabolites biological properties and applications |
ISSN号 | 1660-3397 |
DOI | 10.3390/md15110354 |
文献子类 | Review |
英文摘要 | Nowadays, various drugs on the market are becoming more and more resistant to numerous diseases, thus declining their efficacy for treatment purposes in human beings. Antibiotic resistance is one among the top listed threat around the world which eventually urged the discovery of new potent drugs followed by an increase in the number of deaths caused by cancer due to chemotherapy resistance as well. Accordingly, marine cyanobacteria, being the oldest prokaryotic microorganisms belonging to a monophyletic group, have proven themselves as being able to generate pharmaceutically important natural products. They have long been known to produce distinct and structurally complex secondary metabolites including peptides, polyketides, alkaloids, lipids, and terpenes with potent biological properties and applications. As such, this review will focus on recently published novel compounds isolated from marine cyanobacteria along with their potential bioactivities such as antibacterial, antifungal, anticancer, anti-tuberculosis, immunosuppressive and anti-inflammatory capacities. Moreover, various structural classes, as well as their technological uses will also be discussed. |
WOS关键词 | SP MARINE CYANOBACTERIUM ; MOOREA-PRODUCENS ; OKEANIA SP ; CYCLIC DEPSIPEPTIDES ; LYNGBYA-MAJUSCULA ; DRUG DISCOVERY ; RED-SEA ; A-D ; CHYMOTRYPSIN INHIBITOR ; SECONDARY METABOLITES |
资助项目 | Natural Science Foundation of China[81573306] ; Natural Science Foundation of China[81520108028] ; SCTSM[15431901000] ; SKLDR/SIMM[SIMM 1705ZZ-01] ; NSF of Zhejiang[LY15C200004] |
WOS研究方向 | Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000416600200024 |
出版者 | MDPI AG |
源URL | [http://119.78.100.183/handle/2S10ELR8/272418] ![]() |
专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Wu, Bin; Guo, Yue-Wei |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Zhejiang Univ, Ocean Coll, Hangzhou 310058, Zhejiang, Peoples R China; 3.Zhejiang Gongshang Univ, Dept Appl Chem, Hangzhou 310012, Zhejiang, Peoples R China; |
推荐引用方式 GB/T 7714 | Shah, Sayed Asmat Ali,Akhter, Najeeb,Auckloo, Bibi Nazia,et al. Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review[J]. MARINE DRUGS,2017,15(11). |
APA | Shah, Sayed Asmat Ali.,Akhter, Najeeb.,Auckloo, Bibi Nazia.,Khan, Ishrat.,Lu, Yanbin.,...&Guo, Yue-Wei.(2017).Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review.MARINE DRUGS,15(11). |
MLA | Shah, Sayed Asmat Ali,et al."Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review".MARINE DRUGS 15.11(2017). |
入库方式: OAI收割
来源:上海药物研究所
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