Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides
文献类型：期刊论文
| 作者 | Li, Zhihong1,2,3; Huang, Rong1; Xu, Hongtao1,3; Chen, Jiakang1; Zhan, Yuexiong1; Zhou, Xianhao1; Chen, Hongli1; Jiang, Biao1 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2017-09-15 |
| 卷号 | 19期号:18页码:4972-4975 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.7b02464 |
| 文献子类 | Article |
| 英文摘要 | A new class of N-phenyl-divinylsulfonamides which can be easily prepared have been successfully developed and utilized as efficient linkers in the field of disulfide bond modification. Functional divinylsulfonamides provide opportunities for the specific introduction of various functionalities, including affinity probes, fluorescent tags, and drugs, into peptides. |
| WOS关键词 | CROSS-LINKING ; PROTEIN MODIFICATION ; MACROCYCLIZATION ; CONJUGATION ; PEGYLATION ; BIOCONJUGATION ; EFFICIENT ; POLYMERS ; MALEIMIDES |
| 资助项目 | National Natural Science Foundation of China (NFSC)[21502114] ; China Postdoctoral Science Foundation[2015M581677] ; Open Foundation of the State Key Laboratory of Drug Research, China[SIMM1601KF-05] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000411304300068 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272481]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Chen, Hongli; Jiang, Biao |
| 作者单位 | 1.ShanghaiTech Univ, Shanghai Inst Adv Immunochem Studies, Shanghai 201210, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Li, Zhihong,Huang, Rong,Xu, Hongtao,et al. Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides[J]. ORGANIC LETTERS,2017,19(18):4972-4975. |
| APA | Li, Zhihong.,Huang, Rong.,Xu, Hongtao.,Chen, Jiakang.,Zhan, Yuexiong.,...&Jiang, Biao.(2017).Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides.ORGANIC LETTERS,19(18),4972-4975. |
| MLA | Li, Zhihong,et al."Divinylsulfonamides as Specific Linkers for Stapling Disulfide Bonds in Peptides".ORGANIC LETTERS 19.18(2017):4972-4975. |
入库方式： OAI收割
来源：上海药物研究所
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