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Axiriabilines A-D, uncommon nitrogenous eudesmane-type sesquiterpenes from the Hainan sponge Axinyssa variabilis

文献类型：期刊论文

作者Li, Xu-Wen2; Chen, Si-Han2; Ye, Fei1,2; Mollo, Ernesto3; Zhu, Wei-Liang1,2; Liu, Hai-Li2; Guo, Yue-Wei1,2
刊名TETRAHEDRON
出版日期2017-08-24
卷号73期号:34页码:5239-5243
关键词Sponge Axinyssa variabilis Nitrogenous sesquiterpene Eudesmane South China Sea
ISSN号0040-4020
DOI10.1016/j.tet.2017.07.027
文献子类Article
英文摘要Four new uncommon nitrogenous eudesmane-type sesquiterpenes, axiriabilines A-D (1-4), and two known related ones (5 and 6), were isolated from the Hainan sponge Axinyssa variabilis. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analysis and by comparison of their NMR data with those reported in the literature. The absolute configurations of compounds 1 and 4 were determined by TDDFT ECD calculations. All the new compounds were found to exhibit no cytotoxicity against several cancer cells. (C) 2017 Elsevier Ltd. All rights reserved.
WOS关键词SOUTH CHINA SEA ; ISOCYANIDES ; METABOLITES ; NUDIBRANCH
资助项目Natural Science Foundation of China[41476063] ; Natural Science Foundation of China[81520108028] ; Natural Science Foundation of China[41676073] ; Natural Science Foundation of China[21672230] ; Natural Science Foundation of China[81603022] ; SCTSM Project[15431901000] ; SKLDR/SIMM Projects[SIMM 1705ZZ-01] ; "Youth Innovation Promotion Association" from Chinese Academy of Sciences[2016258] ; "Young Elite Scientists Sponsorship" from China Association for Science and Technology[2016QNRC001] ; Shanghai "Pujiang Program"[16PJ1410600] ; Syngenta-SIMM-PhD Studentship Project[00000000]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000407536500023
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/272523]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Guo, Yue-Wei
作者单位1.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China;
3.CNR, Inst Biomol Chem, Via Campi Flegrei 34, I-80078 Naples, Italy
推荐引用方式
GB/T 7714		 Li, Xu-Wen,Chen, Si-Han,Ye, Fei,et al. Axiriabilines A-D, uncommon nitrogenous eudesmane-type sesquiterpenes from the Hainan sponge Axinyssa variabilis[J]. TETRAHEDRON,2017,73(34):5239-5243.
APA Li, Xu-Wen.,Chen, Si-Han.,Ye, Fei.,Mollo, Ernesto.,Zhu, Wei-Liang.,...&Guo, Yue-Wei.(2017).Axiriabilines A-D, uncommon nitrogenous eudesmane-type sesquiterpenes from the Hainan sponge Axinyssa variabilis.TETRAHEDRON,73(34),5239-5243.
MLA Li, Xu-Wen,et al."Axiriabilines A-D, uncommon nitrogenous eudesmane-type sesquiterpenes from the Hainan sponge Axinyssa variabilis".TETRAHEDRON 73.34(2017):5239-5243.

入库方式： OAI收割

来源：上海药物研究所

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