Transition Metal-Catalyzed Asymmetric Addition of Organoboron Reagents to lmines
文献类型：期刊论文
| 作者 | Chen Diao; Xu Ming-Hua
|
| 刊名 | CHINESE JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2017-07 |
| 卷号 | 37期号:7页码:1589-1612 |
| 关键词 | asymmetric synthesis chiral amine metal catalysis asymmetric addition organoboron |
| ISSN号 | 0253-2786 |
| DOI | 10.6023/cjoc201704017 |
| 文献子类 | Review |
| 英文摘要 | Chiral amines are important building blocks in organic synthesis, they also present in numerous natural products, biologically active compounds and pharmaceutical agents. In recent years, the use of various organoboron reagents in transition metal-catalyzed reactions has attracted considerable attentions because of their ready avilibility, low toxicity, good air and moisture stability as well as high functional group compatibility. This review summarizes the remarkable progress and advances in transition metal-catalyzed asymmetric addition of organoboron reagents to imines over the past few years, providing an overview of the recent achievements in stereoselective synthesis of a-chiral amines by using chiral auxiliary or chiral catalysis strategies. At the present time, rhodium-based asymmetric catalysis has proven to be the most efficient and reliable approach to furnish highly optically active alpha-chiral amines. Varieties of chiral ligands including monophosphines, biphosphines, amidomonophosphanes, phosphoramidites, phosphites, dienes, sulfur-olefins, phosphorus-olefins have showed the great potential in many asymmetric additions of organoboron reagents to imines, enabling the access of both secondary and tertiary a-chiral amines with good to excellent enantioselectivities. On the other hand, important progress has been made in developing effective palladium catalysts mainly based on chiral pyridine-oxazoline and phosphine-oxazoline ligands. However, future studies in this area towards the objective of developing more efficient, practical and general methods remain challenging. |
| WOS关键词 | N-TERT-BUTANESULFINYL ; HIGHLY ENANTIOSELECTIVE ARYLATION ; CHIRAL DIENE LIGANDS ; RECEPTOR-MEDIATED PHENOMENA ; H INSERTION REACTIONS ; ARYLBORONIC ACIDS ; CYCLIC KETIMINES ; SULFONYL KETIMINES ; RH(I)-CATALYZED ADDITION ; IMINO ESTERS |
| 资助项目 | National Natural Science Foundation of China[21325209] ; National Natural Science Foundation of China[21472205] ; Program of Shanghai Academic Research Leaders[14XD1404400] |
| WOS研究方向 | Chemistry |
| 语种 | 中文 |
| CSCD记录号 | CSCD:6046362 |
| WOS记录号 | WOS:000408601000001 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272575]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Xu Ming-Hua |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Diao,Xu Ming-Hua. Transition Metal-Catalyzed Asymmetric Addition of Organoboron Reagents to lmines[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2017,37(7):1589-1612. |
| APA | Chen Diao,&Xu Ming-Hua.(2017).Transition Metal-Catalyzed Asymmetric Addition of Organoboron Reagents to lmines.CHINESE JOURNAL OF ORGANIC CHEMISTRY,37(7),1589-1612. |
| MLA | Chen Diao,et al."Transition Metal-Catalyzed Asymmetric Addition of Organoboron Reagents to lmines".CHINESE JOURNAL OF ORGANIC CHEMISTRY 37.7(2017):1589-1612. |
入库方式： OAI收割
来源：上海药物研究所
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