Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles
文献类型：期刊论文
| 作者 | Ni, Jiabin1,2,3; Zhao, Hongchuan1,2,3; Zhang, Ao1,2,3
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2017-06-16 |
| 卷号 | 19期号:12页码:3159-3162 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.7b01282 |
| 文献子类 | Article |
| 英文摘要 | A novel and efficient C-H activation approach for the direct 3,3-difhioroallylation of 2-pyridones and indoles is herein reported using a manganese(I) complex as the catalyst. A broad range of substrates with diverse functional groups were tolerated. Moreover late-stage C-H functionalization of bioactive molecules was achieved in good yield. |
| WOS关键词 | BOND ACTIVATION ; COBALT CATALYSIS ; DIRECTING GROUPS ; MANGANESE ; FUNCTIONALIZATION ; ALKYNES ; ESTERS ; ACID ; ALKENYLATION ; ALKYNYLATION |
| 资助项目 | Chinese NSF[81430080] ; Chinese NSF[81373277] ; National Program on Key Basic Research Project of China[2015CB910603] ; International Cooperative Program[GJHZ1622] ; Chinese Academy of Sciences[160621] ; Shanghai Commission of Science and Technology[16XD1404600] ; Shanghai Commission of Science and Technology[14431905300] ; Shanghai Commission of Science and Technology[14431900400] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000403854300031 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272603]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Zhang, Ao |
| 作者单位 | 1.Chinese Acad Sci, SIMM, CAS Key Lab Receptor Res, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ni, Jiabin,Zhao, Hongchuan,Zhang, Ao. Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles[J]. ORGANIC LETTERS,2017,19(12):3159-3162. |
| APA | Ni, Jiabin,Zhao, Hongchuan,&Zhang, Ao.(2017).Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles.ORGANIC LETTERS,19(12),3159-3162. |
| MLA | Ni, Jiabin,et al."Manganese(I)-Catalyzed C-H 3,3-Difluoroallylation of Pyridones and Indoles".ORGANIC LETTERS 19.12(2017):3159-3162. |
入库方式： OAI收割
来源：上海药物研究所
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