Clavirolide G, a new rare dolabellane-type diterpenoid from the Xisha soft coral Clavularia viridis
文献类型：期刊论文
| 作者 | Gao, Yuan1; Xiao, Wei3; Liu, Hong-Chun2 ; Wang, Jian-Rong2; Yao, Li-Gong2; Ouyang, Ping-Kai1; Wang, De-Cai1; Guo, Yue-Wei2
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| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2017-04 |
| 卷号 | 28期号:4页码:905-908 |
| 关键词 | Soft coral Clavularia viridis Dolabellane diterpenoid Cytotoxic activity |
| ISSN号 | 1001-8417 |
| DOI | 10.1016/j.cclet.2017.01.004 |
| 文献子类 | Article |
| 英文摘要 | One new dolabellane-type diterpenoid, named clavirolide G (1), and one known related analogue (3), have been isolated from the soft coral Clavularia viridis collected off the Xisha Islands in the South China Sea. Its structure and absolute configuration were determined on the basis of spectroscopic analysis, electronic circular dichroism, and compared with literature model compounds. The cytotoxic activity of these two compounds was evaluated against a panel of human tumor cell lines. Compound 1 showed moderate cytotoxic activity against KB and HL-60 cells. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved. |
| WOS关键词 | SARCOPHYTON-TROCHELIOPHORUM MARENZELLER ; MARINE DITERPENOIDS ; NATURAL-PRODUCTS ; ASSAY |
| 资助项目 | National Natural Science Foundation of China[81520108028] ; National Natural Science Foundation of China[21672230] ; National Natural Science Foundation of China[41506187] ; National Natural Science Foundation of China[816013016] ; SKLDR/SIMM Project[SIMM1501ZZ-03] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5990223 |
| WOS记录号 | WOS:000402214400035 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272713]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Wang, De-Cai; Guo, Yue-Wei |
| 作者单位 | 1.Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, Nanjing 211816, Jiangsu, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Jiangsu Kan Pharmaceut Co Ltd, Lianyungang 222002, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Yuan,Xiao, Wei,Liu, Hong-Chun,et al. Clavirolide G, a new rare dolabellane-type diterpenoid from the Xisha soft coral Clavularia viridis[J]. CHINESE CHEMICAL LETTERS,2017,28(4):905-908. |
| APA | Gao, Yuan.,Xiao, Wei.,Liu, Hong-Chun.,Wang, Jian-Rong.,Yao, Li-Gong.,...&Guo, Yue-Wei.(2017).Clavirolide G, a new rare dolabellane-type diterpenoid from the Xisha soft coral Clavularia viridis.CHINESE CHEMICAL LETTERS,28(4),905-908. |
| MLA | Gao, Yuan,et al."Clavirolide G, a new rare dolabellane-type diterpenoid from the Xisha soft coral Clavularia viridis".CHINESE CHEMICAL LETTERS 28.4(2017):905-908. |
入库方式： OAI收割
来源：上海药物研究所
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