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Efficient Iron-Catalyzed N-Arylation of Aryl Halides with Amines

文献类型：期刊论文

作者Guo, Diliang1,2; Huang, He2; Xu, Jinyi1; Jiang, Hualiang2,3; Liu, Hong2
刊名ORGANIC LETTERS
出版日期2008-10-16
卷号10期号:20页码:4513-4516
ISSN号1523-7060
DOI10.1021/ol801784a
文献子类Article
英文摘要A practical and promising protocol was developed for N-arylations of various amines with differently substituted aryl halides. The processes are efficiently promoted by the catalyst system involving the environmentally benign Fe2O3 and the universal ligand L-proline. The versatility, convenient operation, low cost, and environmental friendliness, in combination with the high yields, render this method viable for use in both laboratory research and larger industrial scales.
WOS关键词CROSS-COUPLING REACTIONS ; BOND-FORMING REACTIONS ; NITROGEN NUCLEOPHILES ; ALIPHATIC-AMINES ; COPPER ; BROMIDES ; ELIMINATION ; IODIDES ; CARBON
资助项目State Key Program of Basic Research of China[2006BAI01B02] ; National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[20872153] ; Talent Research Group from the Shanghai Science and Technology Commission[00000000] ; 863 Hi-Tech Program of China[2006AA020602]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000259940600031
出版者AMER CHEMICAL SOC
源URL[http://119.78.100.183/handle/2S10ELR8/272779]  
专题药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
药物发现与设计中心
通讯作者Liu, Hong
作者单位1.China Pharmaceut Univ, Dept Med Chem, Nanjing 210009, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, State Key Lab Drug Res,Durg Discovery & Design Ct, Shanghai 201203, Peoples R China;
3.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
推荐引用方式
GB/T 7714		 Guo, Diliang,Huang, He,Xu, Jinyi,et al. Efficient Iron-Catalyzed N-Arylation of Aryl Halides with Amines[J]. ORGANIC LETTERS,2008,10(20):4513-4516.
APA Guo, Diliang,Huang, He,Xu, Jinyi,Jiang, Hualiang,&Liu, Hong.(2008).Efficient Iron-Catalyzed N-Arylation of Aryl Halides with Amines.ORGANIC LETTERS,10(20),4513-4516.
MLA Guo, Diliang,et al."Efficient Iron-Catalyzed N-Arylation of Aryl Halides with Amines".ORGANIC LETTERS 10.20(2008):4513-4516.

入库方式： OAI收割

来源：上海药物研究所

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