Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia
文献类型：期刊论文
| 作者 | Ciavatta, Maria Letizia1; Pilar Lopez-Gresa, M.2; Gavagnin, Margherita1; Nicoletti, Rosario3; Manzo, Emiliano1; Mollo, Ernesto1; Guo, Yue-Wei4 ; Cimino, Guido1
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| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2008-05-26 |
| 卷号 | 64期号:22页码:5365-5369 |
| 关键词 | hexahydrobenzopyrane derivatives cytosporins marine fungus Eutypella scoporia carbonate NMR Mosher method pulmonata |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2008.03.016 |
| 文献子类 | Article |
| 英文摘要 | Chemical investigation of the culture broth of the fungus Eutypella scoparia ICB-OBX, isolated from the marine pulmonate mollusc Onchidium sp., led to the finding of novel compounds 1 and 2, structurally related to angiotensin II binding inhibitors cytosporins, along with unrelated known nitrogen metabolites (compounds 3-5). The structure and the relative stereochemistry of the novel metabolites were assigned mainly by a detailed analysis of two-dimensional NMR techniques whereas the absolute stereochemistry was proposed by modified Mosher's method. Compound 2 contains an unusual cyclic carbonate functionality that is rare among natural products. (C) 2008 Elsevier Ltd. All rights reserved. |
| WOS关键词 | LIPID DROPLET FORMATION ; ABSOLUTE-CONFIGURATIONS ; ENDOPHYTIC FUNGUS ; MOUSE MACROPHAGES ; MOSHER METHOD ; SEA HARE ; METABOLITES ; PHENOCHALASINS ; POLYKETIDES ; INHIBITORS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000256179700063 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/272916]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Ciavatta, Maria Letizia |
| 作者单位 | 1.CNR, Ist Chim Biomol, I-80078 Pozzuoli, Italy; 2.Univ Politecn Valencia, Ctr Ecol Quim Agricola, Valencia 46022, Spain; 3.CRA, Ist Sperimentale Tabacco, I-84018 Scafati, Italy; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Inst Biol Sci, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ciavatta, Maria Letizia,Pilar Lopez-Gresa, M.,Gavagnin, Margherita,et al. Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia[J]. TETRAHEDRON,2008,64(22):5365-5369. |
| APA | Ciavatta, Maria Letizia.,Pilar Lopez-Gresa, M..,Gavagnin, Margherita.,Nicoletti, Rosario.,Manzo, Emiliano.,...&Cimino, Guido.(2008).Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia.TETRAHEDRON,64(22),5365-5369. |
| MLA | Ciavatta, Maria Letizia,et al."Cytosporin-related compounds from the marine-derived fungus Eutypella scoparia".TETRAHEDRON 64.22(2008):5365-5369. |
入库方式： OAI收割
来源：上海药物研究所
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