Water-soluble constituents of the root barks of Fraxinus rhynchophylla (Chinese drug Qinpi)
文献类型:期刊论文
作者 | Xiao, Kai1,2; Song, Qing-Hong1; Zhang, Shu-Wei1; Xuan, Li-Jiang1![]() |
刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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出版日期 | 2008 |
卷号 | 10期号:2页码:205-210 |
关键词 | Fraxinus rhynchophylla Oleaceae fraxisecoside PTP1B inhibition activity |
ISSN号 | 1028-6020 |
DOI | 10.1080/10286020701394514 |
文献子类 | Article |
英文摘要 | Chemical studies on the roots of Fraxinus rhynchophylla led to the isolation of fraxisecoside (1), a novel coumarin-secoiridoid hybrid glycoside, namely, fraxetin-8-O-[11'-methyl-oleosidyl-(7' -> 6 '')]-beta-Dglucopyranoside and 14 known compounds. Their structures were elucidated based on chemical evidence and spectroscopic analysis, including extensive 2D NMR methods. Compound 2 was first isolated as a pure compound. Compound 1 exhibited moderate PTP1B inhibition activity. Compounds 1 and 2 showed inhibition activity against B- and T-cell proliferation, without cytotoxicity. |
WOS关键词 | SECOIRIDOID GLUCOSIDES ; GLYCOSIDES |
WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000256384400015 |
出版者 | TAYLOR & FRANCIS LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/273048] ![]() |
专题 | 上海中药现代化研究中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Xuan, Li-Jiang |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.Second Mil Med Univ, Fac Naval Med, Lab Toxin & Pharmarmacol, Shanghai 200433, Peoples R China |
推荐引用方式 GB/T 7714 | Xiao, Kai,Song, Qing-Hong,Zhang, Shu-Wei,et al. Water-soluble constituents of the root barks of Fraxinus rhynchophylla (Chinese drug Qinpi)[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2008,10(2):205-210. |
APA | Xiao, Kai,Song, Qing-Hong,Zhang, Shu-Wei,&Xuan, Li-Jiang.(2008).Water-soluble constituents of the root barks of Fraxinus rhynchophylla (Chinese drug Qinpi).JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,10(2),205-210. |
MLA | Xiao, Kai,et al."Water-soluble constituents of the root barks of Fraxinus rhynchophylla (Chinese drug Qinpi)".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 10.2(2008):205-210. |
入库方式: OAI收割
来源:上海药物研究所
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