Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes
文献类型：期刊论文
| 作者 | Manzo, Emiliano; Gavagnin, Margherita; Somerville, Michael J.; Mao, Shui-Chun; Ciavatta, M. Letizia; Mollo, Ernesto; Schupp, Peter J.; Garson, Mary J.; Guo, Yue-Wei ; Cimino, Guido
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| 刊名 | JOURNAL OF CHEMICAL ECOLOGY
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| 出版日期 | 2007-12 |
| 卷号 | 33期号:12页码:2325-2336 |
| 关键词 | Opisthobranchia Chromodorididae Glossodoris sesterterpenoids scalaranes |
| ISSN号 | 0098-0331 |
| DOI | 10.1007/s10886-007-9387-x |
| 文献子类 | Article |
| 英文摘要 | With the aim of establishing whether the oxidation of the tricyclic carbon skeleton of scalaradial (1) is specific to Glossodoris mollusks, the chemical investigation of specimens of Glossodoris pallida from two distinct geographical areas (China and Guam) and of Glossodoris vespa and Glossodoris averni from Eastern Australia was performed. 12-Deacetoxy-12-oxo-scalaradial (4), recently reported from another Glossodoris nudibranch, was the main metabolite of G. pallida from China, G. vespa, and G. averni. A series of scalarane compounds 3 and 5-11, including the unprecedented 12,16-deacetoxy-12-oxo-scalarafuran 5, was isolated from the mollusks. Interestingly, a population of G. pallida from Guam displayed a different scalarane pattern that was characterized by scalaradial (1), deacetyl scalaradial (2), and deoxoscalarin (3), thus confirming previous reports. The specific occurrence of 12-keto-derivatives in some nudibranchs of the genus Glossodoris is discussed. |
| WOS关键词 | CYTOTOXIC SESTERTERPENOIDS ; CHROMODORIS-INORNATA ; SPONGIA-OFFICINALIS ; ATROMARGINATA ; METABOLITES ; ECOLOGY |
| 资助项目 | NIGMS NIH HHS[SO6-GM-4479615] ; NIGMS NIH HHS[SO6-GM-44796-16A] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000251425900013 |
| 出版者 | SPRINGER |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273106]  |
| 专题 | 新药研究国家重点实验室 中科院受体结构与功能重点实验室 |
| 通讯作者 | Gavagnin, Margherita |
| 作者单位 | 1.Univ Guam, Marine Lab, UOG Stn, Mangilao, GU 96923 USA 2.CNR, Inst Chim Biomol, I-80078 Pozzuoli, Italy 3.Univ Queensland, Sch Mol & Microbiol Sci, Brisbane, Qld 4072, Australia 4.Chinese Acad Sci, Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Manzo, Emiliano,Gavagnin, Margherita,Somerville, Michael J.,et al. Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes[J]. JOURNAL OF CHEMICAL ECOLOGY,2007,33(12):2325-2336. |
| APA | Manzo, Emiliano.,Gavagnin, Margherita.,Somerville, Michael J..,Mao, Shui-Chun.,Ciavatta, M. Letizia.,...&Cimino, Guido.(2007).Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes.JOURNAL OF CHEMICAL ECOLOGY,33(12),2325-2336. |
| MLA | Manzo, Emiliano,et al."Chemistry of Glossodoris nudibranchs: Specific occurrence of 12-keto scalaranes".JOURNAL OF CHEMICAL ECOLOGY 33.12(2007):2325-2336. |
入库方式： OAI收割
来源：上海药物研究所
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