Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela
文献类型:期刊论文
作者 | Manzo, Emiliano2; Gavagnin, Margherita2; Bifulco, Giuseppe3; Cimino, Paola3; Di Micco, Simone3; Ciavatta, M. Letizia2; Guo, Yue Wei1; Cimino, Guido2 |
刊名 | TETRAHEDRON
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出版日期 | 2007-10-01 |
卷号 | 63期号:40页码:9970-9978 |
关键词 | marine natural products molluscs aplysiol absolute stereochemistry |
ISSN号 | 0040-4020 |
DOI | 10.1016/j.tet.2007.07.055 |
文献子类 | Article |
英文摘要 | Two novel triterpenoids, aplysiols A (5) and B (6), have been isolated, together with structurally related known metabolites, from a South China Sea collection of the anaspidean mollusc Aplysia dactylomela. The structures of 5 and 6 were determined mainly by spectroscopic NMR techniques. The absolute stereochemistry of compound 5 was deduced by Mosher's method as well as by biogenetical consideration, whereas the absolute stereochemistry of compound 6 was established also using an integrated NMR-QM (Quantum Mechanical) approach, based on the combination of C-13 NMR chemical shifts and (2,3)JC-H coupling constant DFT (density functional theory) calculations. (c) 2007 Published by Elsevier Ltd. |
WOS关键词 | NATURAL-PRODUCTS ; THYRSIFERYL 23-ACETATE ; ORGANIC-COMPOUNDS ; LAURENCIA ; NMR ; CONFIGURATION ; VENUSTATRIOL ; SPECTRA ; (+)-VENUSTATRIOL ; (+)-THYRSIFEROL |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000252092100006 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/273147] ![]() |
专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Manzo, Emiliano |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.CNR, Ist Chim Biomol, I-80078 Naples, Italy; 3.Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Salerno, Italy; |
推荐引用方式 GB/T 7714 | Manzo, Emiliano,Gavagnin, Margherita,Bifulco, Giuseppe,et al. Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela[J]. TETRAHEDRON,2007,63(40):9970-9978. |
APA | Manzo, Emiliano.,Gavagnin, Margherita.,Bifulco, Giuseppe.,Cimino, Paola.,Di Micco, Simone.,...&Cimino, Guido.(2007).Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela.TETRAHEDRON,63(40),9970-9978. |
MLA | Manzo, Emiliano,et al."Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela".TETRAHEDRON 63.40(2007):9970-9978. |
入库方式: OAI收割
来源:上海药物研究所
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