中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela

文献类型:期刊论文

作者Manzo, Emiliano2; Gavagnin, Margherita2; Bifulco, Giuseppe3; Cimino, Paola3; Di Micco, Simone3; Ciavatta, M. Letizia2; Guo, Yue Wei1; Cimino, Guido2
刊名TETRAHEDRON
出版日期2007-10-01
卷号63期号:40页码:9970-9978
关键词marine natural products molluscs aplysiol absolute stereochemistry
ISSN号0040-4020
DOI10.1016/j.tet.2007.07.055
文献子类Article
英文摘要Two novel triterpenoids, aplysiols A (5) and B (6), have been isolated, together with structurally related known metabolites, from a South China Sea collection of the anaspidean mollusc Aplysia dactylomela. The structures of 5 and 6 were determined mainly by spectroscopic NMR techniques. The absolute stereochemistry of compound 5 was deduced by Mosher's method as well as by biogenetical consideration, whereas the absolute stereochemistry of compound 6 was established also using an integrated NMR-QM (Quantum Mechanical) approach, based on the combination of C-13 NMR chemical shifts and (2,3)JC-H coupling constant DFT (density functional theory) calculations. (c) 2007 Published by Elsevier Ltd.
WOS关键词NATURAL-PRODUCTS ; THYRSIFERYL 23-ACETATE ; ORGANIC-COMPOUNDS ; LAURENCIA ; NMR ; CONFIGURATION ; VENUSTATRIOL ; SPECTRA ; (+)-VENUSTATRIOL ; (+)-THYRSIFEROL
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000252092100006
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/273147]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Manzo, Emiliano
作者单位1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
2.CNR, Ist Chim Biomol, I-80078 Naples, Italy;
3.Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Salerno, Italy;
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Manzo, Emiliano,Gavagnin, Margherita,Bifulco, Giuseppe,et al. Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela[J]. TETRAHEDRON,2007,63(40):9970-9978.
APA Manzo, Emiliano.,Gavagnin, Margherita.,Bifulco, Giuseppe.,Cimino, Paola.,Di Micco, Simone.,...&Cimino, Guido.(2007).Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela.TETRAHEDRON,63(40),9970-9978.
MLA Manzo, Emiliano,et al."Aplysiols A and B, squalene-derived polyethers from the mantle of the sea hare Aplysia dactylomela".TETRAHEDRON 63.40(2007):9970-9978.

入库方式: OAI收割

来源:上海药物研究所

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