Total synthesis of gymnorrhizol, an unprecedented 15-membered macrocyclic polydisulfide from the Chinese mangrove Bruguiera gymnorrhiza
文献类型：期刊论文
| 作者 | Gong, Jing-Xu; Shen, Xu ; Yao, Li-Gong; Jiang, Hualiang; Krohn, Karsten; Guo, Yue-Wei
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2007-04-26 |
| 卷号 | 9期号:9页码:1715-1716 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol0703783 |
| 文献子类 | Article |
| 英文摘要 | The total synthesis of gymnorrhizol, a naturally occurring macrocyclic polydisulfide with a new skeleton and a potent proteintyrosinephosphatase 1B inhibitor, was prepared in three steps, starting from (R)-1-bromo-3-chloroisopropanol and 1,3-dichloropropan-2-ol. |
| WOS关键词 | CONVENIENT SYNTHESIS ; INSULIN SENSITIVITY ; LISSOCLINOTOXIN-A ; DISULFIDES ; OXIDATION ; THIOLS ; DERIVATIVES ; ALKALOIDS ; VARACIN ; MICE |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000245799200025 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273280]  |
| 专题 | 药理学第三研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物发现与设计中心 天然药物化学研究室 |
| 通讯作者 | Gong, Jing-Xu |
| 作者单位 | 1.Univ Paderborn, Dept Chem, D-33098 Paderborn, Germany 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gong, Jing-Xu,Shen, Xu,Yao, Li-Gong,et al. Total synthesis of gymnorrhizol, an unprecedented 15-membered macrocyclic polydisulfide from the Chinese mangrove Bruguiera gymnorrhiza[J]. ORGANIC LETTERS,2007,9(9):1715-1716. |
| APA | Gong, Jing-Xu,Shen, Xu,Yao, Li-Gong,Jiang, Hualiang,Krohn, Karsten,&Guo, Yue-Wei.(2007).Total synthesis of gymnorrhizol, an unprecedented 15-membered macrocyclic polydisulfide from the Chinese mangrove Bruguiera gymnorrhiza.ORGANIC LETTERS,9(9),1715-1716. |
| MLA | Gong, Jing-Xu,et al."Total synthesis of gymnorrhizol, an unprecedented 15-membered macrocyclic polydisulfide from the Chinese mangrove Bruguiera gymnorrhiza".ORGANIC LETTERS 9.9(2007):1715-1716. |
入库方式： OAI收割
来源：上海药物研究所
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