Rapid identification of bibenzyls of Stemona sessilifolia using hyphenated LC-UV-NMR and LGMS methods
文献类型：期刊论文
| 作者 | Yang Xin-zhou; Yang Yi-ping ; Tang Chun-ping; Ke Chang-qiang; Ye Yang
|
| 刊名 | CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
 |
| 出版日期 | 2007-01 |
| 卷号 | 23期号:1页码:48-51 |
| 关键词 | bibenzyls LC-UV-NMR Stemona sessilifolia |
| ISSN号 | 1005-9040 |
| DOI | 10.1016/S1005-9040(07)60010-5 |
| 文献子类 | Article |
| 英文摘要 | As a part of the ongoing search for new constituents of Stemona species in China, chemical investigation of Stemona sessilifolia, a plant used in the traditional Chinese medicine to treat respiratory disorders, was carried out. To identify the chemical components rapidly, a selected sample of S. sessilifolia containing bibenzyls was tested using LC-ESIMS and analyzed further using stop-flow LC-UV-NMR, which was sensitive for the detection of the main constituents. LC microfractions were collected using the LC-UV-NMR technique and HR-EIMS off-line analysis was carried out on the collected fractions. This chemical screening strategy allowed for the on-line identification of the main constituents of S. sessilifolia and provided information that was useful for a further peak-guided isolation procedure. Using these methods, four bibenzyls were isolated: two known compounds, 3,5-dihydroxy-4-methyl bibenzyl(1) and 3, 5-dihydroxy-2'-methoxy-4-methyl bibenzyl ( 2), and two novel compounds, 3, 3'-dihydroxy-5, 6'-dimethoxy bibenzyl(3) and 3,5-dihydroxy-2',5'-dimethoxy bibenzyl(4). |
| WOS关键词 | MAGNETIC-RESONANCE-SPECTROSCOPY ; LIQUID-CHROMATOGRAPHY ; MASS-SPECTROMETRY ; ALKALOIDS ; TUBEROSA ; JAPONICA |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3005660 |
| WOS记录号 | WOS:000244006800010 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273367]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Ye Yang |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang Xin-zhou,Yang Yi-ping,Tang Chun-ping,et al. Rapid identification of bibenzyls of Stemona sessilifolia using hyphenated LC-UV-NMR and LGMS methods[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2007,23(1):48-51. |
| APA | Yang Xin-zhou,Yang Yi-ping,Tang Chun-ping,Ke Chang-qiang,&Ye Yang.(2007).Rapid identification of bibenzyls of Stemona sessilifolia using hyphenated LC-UV-NMR and LGMS methods.CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,23(1),48-51. |
| MLA | Yang Xin-zhou,et al."Rapid identification of bibenzyls of Stemona sessilifolia using hyphenated LC-UV-NMR and LGMS methods".CHEMICAL RESEARCH IN CHINESE UNIVERSITIES 23.1(2007):48-51. |
入库方式： OAI收割
来源：上海药物研究所
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