Two new 18-carbon norditerpenoid alkaloids from Aconitum sinomontanum
文献类型：期刊论文
| 作者 | Tan, J. -J.; Tan, Changheng1 ; Ruan, B. -Q.; Jiang, Shanhao; Zhu, Dayuan1
|
| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2006-09 |
| 卷号 | 8期号:6页码:535-539 |
| 关键词 | sinaconitine A sinaconitine B norditerpenoid alkaloid Aconitum sinomontanum |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020500175643 |
| 文献子类 | Article |
| 英文摘要 | Two new 18-carbon norditerpenoid alkaloids, sinaconitines A (1) and B (2), together with two known alkaloids, ranaconitine (3) and lappaconitine (4), were isolated from the roots of Aconitum sinomontanum. Their structures were elucidated on the basis of spectral evidences and X-ray crystallographic analysis for 1. Furthermore, the reversed C-13 NMR assignments for C-10 and C-13 of 3, 4, puberanine, puberanidine and demethyllappaconitine were revised. Compounds 1-4 were evaluated for cyclooxygenase-2 (COX-2) enzyme inhibitory activity. However, they did not show any inhibition at 10 mu M. |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000239999600011 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273508]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Zhu, Dayuan |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Fujian Inst Drug Control, Fuzhou 350001, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tan, J. -J.,Tan, Changheng,Ruan, B. -Q.,et al. Two new 18-carbon norditerpenoid alkaloids from Aconitum sinomontanum[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2006,8(6):535-539. |
| APA | Tan, J. -J.,Tan, Changheng,Ruan, B. -Q.,Jiang, Shanhao,&Zhu, Dayuan.(2006).Two new 18-carbon norditerpenoid alkaloids from Aconitum sinomontanum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,8(6),535-539. |
| MLA | Tan, J. -J.,et al."Two new 18-carbon norditerpenoid alkaloids from Aconitum sinomontanum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 8.6(2006):535-539. |
入库方式： OAI收割
来源：上海药物研究所
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