Secondary Metabolites from the South China Sea Invertebrates: Chemistry and Biological Activity
文献类型：期刊论文
| 作者 | Zhang, Wen1; Guo, Yue-Wei1 ; Gu, Yucheng2
|
| 刊名 | CURRENT MEDICINAL CHEMISTRY
 |
| 出版日期 | 2006-07 |
| 卷号 | 13期号:17页码:2041-2090 |
| 关键词 | The South China Sea secondary metabolites invertebrates terpenoids steroids alkaloids bioactivity cancer cell lines |
| ISSN号 | 0929-8673 |
| DOI | 10.2174/092986706777584960 |
| 文献子类 | Review |
| 英文摘要 | The increasing demand for new lead compounds in the pharmaceutical and agrochemical industries has driven scientists to search for new sources of bioactive natural products. Marine invertebrates are a rich source of novel, bioactive secondary metabolites and they have attracted a great deal of attention from scientists in the fields of chemistry, pharmacology, ecology, and molecular biology. During the past 25 years, many complex and structurally unique secondary metabolites have been isolated from the invertebrates inhabiting the South China Sea. These metabolites are responsible for various bioactivities such as anti-tumor, anti-inflammation and antioxidant activities, and/or they act on the cardiovascular system. This review will focus on the marine natural product chemistry of invertebrates from the South China Sea, aiming to give the reader a brief view of the compounds isolated from these invertebrates, as well as their biological activities. The article covers the literature published during the period from the beginning of 1980 to the end of 2005, with 340 citations and 811 compounds from invertebrates from the South China Sea, including sponges, coelenterates, molluscs and echinoderms. |
| 资助项目 | National Marine 863 Project[2005AA624040] ; Natural Science Foundation of China[20572116] ; STCSM Project[04ZR14156] ; STCSM Project[054307062] ; State Key Program of Basic Research of China[2004CB518905] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000207523900006 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273553]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Guo, Yue-Wei |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Drug Res, Inst Mat Med, Shanghai 201203, Peoples R China; 2.Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England |
| 推荐引用方式 GB/T 7714 | Zhang, Wen,Guo, Yue-Wei,Gu, Yucheng. Secondary Metabolites from the South China Sea Invertebrates: Chemistry and Biological Activity[J]. CURRENT MEDICINAL CHEMISTRY,2006,13(17):2041-2090. |
| APA | Zhang, Wen,Guo, Yue-Wei,&Gu, Yucheng.(2006).Secondary Metabolites from the South China Sea Invertebrates: Chemistry and Biological Activity.CURRENT MEDICINAL CHEMISTRY,13(17),2041-2090. |
| MLA | Zhang, Wen,et al."Secondary Metabolites from the South China Sea Invertebrates: Chemistry and Biological Activity".CURRENT MEDICINAL CHEMISTRY 13.17(2006):2041-2090. |
入库方式： OAI收割
来源：上海药物研究所
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