Two novel aromatic valerenane-type sesquiterpenes from the Chinese green alga Caulerpa taxifolia
文献类型：期刊论文
| 作者 | Mao, SC; Guo, YW ; Shen, X
|
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2006-06-01 |
| 卷号 | 16期号:11页码:2947-2950 |
| 关键词 | green alga Caulerpa taxifolia aromatic valerenane-type sesquiterpenes cauterpal A and B |
| ISSN号 | 0960-894X |
| DOI | 10.1016/j.bmcl.2006.02.074 |
| 文献子类 | Article |
| 英文摘要 | Caulerpal A (2) and B (3), two novel sesquiterpenes possessing an uncommon aromatic valerenane-type carbon skeleton, along with one known metabolite, caulerpin (4), have been isolated from the Chinese green alga Caulerpa taxifolia (Vahl) C. Agardh. Their structures and relative stereochemistry were elucidated on the basis of extensive spectroscopic analysis. Compounds 2-4 were evaluated for their inhibitory activity against hPTP1B and the result showed that only compound 4 had a strong PTP1B inhibitory activity with an IC50 value of 3.77 mu M. (c) 2006 Elsevier Ltd. All rights reserved. |
| WOS关键词 | TERPENES ; ACID |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000237407800025 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273570]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Guo, YW |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mao, SC,Guo, YW,Shen, X. Two novel aromatic valerenane-type sesquiterpenes from the Chinese green alga Caulerpa taxifolia[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2006,16(11):2947-2950. |
| APA | Mao, SC,Guo, YW,&Shen, X.(2006).Two novel aromatic valerenane-type sesquiterpenes from the Chinese green alga Caulerpa taxifolia.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,16(11),2947-2950. |
| MLA | Mao, SC,et al."Two novel aromatic valerenane-type sesquiterpenes from the Chinese green alga Caulerpa taxifolia".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16.11(2006):2947-2950. |
入库方式： OAI收割
来源：上海药物研究所
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