New selective O-debenzylation of phenol with Mg/MeOH
文献类型:期刊论文
作者 | Huang, W; Zhang, X; Liu, H![]() ![]() ![]() |
刊名 | TETRAHEDRON LETTERS
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出版日期 | 2005-08-29 |
卷号 | 46期号:35页码:5965-5967 |
关键词 | substituted benzyl phenol protecting group selective O-debenzylation Mg/MeOH |
ISSN号 | 0040-4039 |
DOI | 10.1016/j.tetlet.2005.06.046 |
文献子类 | Article |
英文摘要 | Carboxylate-benzyl and nitro-benzyl groups used in phenols protection were selectively debenzylated with 3-25 equiv of Mg in methanol at room temperature. Good yields of the desired phenols were obtained within 3-10 h from a wide variety of O-(carboxylate-benzyl)- or O-(nitro-benzyl)-phenols. Selective O-debenzylation was possible in the presence of O-(carboxylate-benzyl)- or O-(nitro-benzyl)-phenols with Mg/MeOH. (c) 2005 Published by Elsevier Ltd. |
WOS关键词 | OXIDATIVE DEBENZYLATION |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000231209000040 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/273814] ![]() |
专题 | 药物发现与设计中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Jiang, HL |
作者单位 | 1.Chinese Acad Sci, Ctr Drug Discovery & Design, State Key Lab Drug Res, Shanghai Inst Mat Med,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 201203, Peoples R China 3.Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Liaoning, Peoples R China 4.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
推荐引用方式 GB/T 7714 | Huang, W,Zhang, X,Liu, H,et al. New selective O-debenzylation of phenol with Mg/MeOH[J]. TETRAHEDRON LETTERS,2005,46(35):5965-5967. |
APA | Huang, W,Zhang, X,Liu, H,Shen, JH,&Jiang, HL.(2005).New selective O-debenzylation of phenol with Mg/MeOH.TETRAHEDRON LETTERS,46(35),5965-5967. |
MLA | Huang, W,et al."New selective O-debenzylation of phenol with Mg/MeOH".TETRAHEDRON LETTERS 46.35(2005):5965-5967. |
入库方式: OAI收割
来源:上海药物研究所
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