中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Is there a better source of huperzine A than Huperzia serrata? Huperzine A content of huperziaceae species in China

文献类型:期刊论文

作者Ma, XQ; Tan, CH; Zhu, DY; Gang, DR
刊名JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
出版日期2005-03-09
卷号53期号:5页码:1393-1398
关键词huperzine A Huperzia Phlegmariurus RP-HPLC Huperziaceae traditional medicine medicinal plant
ISSN号0021-8561
DOI10.1021/jf048193n
文献子类Article
英文摘要A precise and selective reversed phase high-performance liquid chromatographic method was developed for quantifying huperzine A (HupA) in samples of the Huperziaceae in China. This method was used to quantify the levels of HupA in samples of Huperzia serrata collected from a single population at different times of the year, in different organs of the same H. serrata plant, and from different geographical locations of H. serrata plants in China. For different species of Huperziaceae, the highest content of HupA was found in Phlegmariurus carinatus. Members of the genus Phlegmariurus possessed higher levels of HupA than Huperzia species. H. serrata plants growing in humid forests contained significantly more HupA than plants growing in less humid environments. Finally, HupA content varied significantly by season, with the highest levels being found in mid fall and the lowest levels in early spring, suggesting that HupA is turned over in the plant.
WOS关键词ALZHEIMERS-DISEASE ; ALKALOIDS ; DRUG
WOS研究方向Agriculture ; Chemistry ; Food Science & Technology
语种英语
WOS记录号WOS:000227391300013
出版者AMER CHEMICAL SOC
源URL[http://119.78.100.183/handle/2S10ELR8/273895]  
专题新药研究国家重点实验室
中科院受体结构与功能重点实验室
通讯作者Ma, XQ
作者单位1.Univ Arizona, Dept Plant Sci, Tucson, AZ 85721 USA
2.Univ Arizona, Bio5 Inst, Tucson, AZ 85721 USA
3.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
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GB/T 7714
Ma, XQ,Tan, CH,Zhu, DY,et al. Is there a better source of huperzine A than Huperzia serrata? Huperzine A content of huperziaceae species in China[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2005,53(5):1393-1398.
APA Ma, XQ,Tan, CH,Zhu, DY,&Gang, DR.(2005).Is there a better source of huperzine A than Huperzia serrata? Huperzine A content of huperziaceae species in China.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,53(5),1393-1398.
MLA Ma, XQ,et al."Is there a better source of huperzine A than Huperzia serrata? Huperzine A content of huperziaceae species in China".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 53.5(2005):1393-1398.

入库方式: OAI收割

来源:上海药物研究所

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