Catechol-bisphosphonate conjugates: New potential chelating agents for metal intoxication therapy
文献类型：期刊论文
| 作者 | Xu, GY; Yang, CH ; Liu, B; Wu, XH; Xie, YY
|
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2004-12 |
| 卷号 | 15期号:12页码:1403-1406 |
| 关键词 | bisphosphonates catechol chelating agents metal intoxication therapy |
| ISSN号 | 1001-8417 |
| 文献子类 | Article |
| 英文摘要 | In a quest for better chelating therapy drugs for the treatment of intoxication by Fe, Al, or actinides, two new series of mixed catechol-bisphosphonate through amide linkage were synthesized. Benzyl group was used as protecting group to avoid the breakage of amide by acid hydrolysis or incomplete reaction in silylation-dealkylation using bromotrimethylsilane. |
| WOS关键词 | 1-PHENYL-1-HYDROXYMETHYLENE BISPHOSPHONATE ; ANALOGS ; ACID |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000225807800007 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273984]  |
| 专题 | 国家新药筛选中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 上海中药现代化研究中心 |
| 通讯作者 | Wu, XH |
| 作者单位 | Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, GY,Yang, CH,Liu, B,et al. Catechol-bisphosphonate conjugates: New potential chelating agents for metal intoxication therapy[J]. CHINESE CHEMICAL LETTERS,2004,15(12):1403-1406. |
| APA | Xu, GY,Yang, CH,Liu, B,Wu, XH,&Xie, YY.(2004).Catechol-bisphosphonate conjugates: New potential chelating agents for metal intoxication therapy.CHINESE CHEMICAL LETTERS,15(12),1403-1406. |
| MLA | Xu, GY,et al."Catechol-bisphosphonate conjugates: New potential chelating agents for metal intoxication therapy".CHINESE CHEMICAL LETTERS 15.12(2004):1403-1406. |
入库方式： OAI收割
来源：上海药物研究所
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