Kinetics of the Phenotype and Function of Murine Peritoneal Macrophages Following Acute Inflammation
文献类型：期刊论文
| 作者 | Wu, Qingli1,2; Feng, Yonghong1,2; Yang, Yifu1,2; Liu, Jing1,2; Zhou, Wenliang1,2; He, Peilan1,2; Zhou, Ru1,2; Li, Xiaoyu1,2; Zou, Jianping1,2 |
| 刊名 | CELLULAR & MOLECULAR IMMUNOLOGY
 |
| 出版日期 | 2004-02 |
| 卷号 | 1期号:1页码:57-62 |
| 关键词 | macrophage cytokine phenotype self-regulation |
| ISSN号 | 1672-7681 |
| 文献子类 | Article |
| 英文摘要 | This study was undertaken to have a better understand for the process and the underlying mechanisms to limit macrophage activation and population of activated macrophages. A comprehensive kinetics of cytokine production was performed in murine peritoneal macrophages recovered from Balb/c mice at various time during the course of an intraperitoneal injection with thioglycollate (TG). The expression of cell surface molecules such as MHC-I, MHC-II, B7-1 and B7-2 of these macrophages were also determined by flow cytometry. The present findings of our research suggested that the population of activated macrophages and the activation of macrophages (including cytokines production and expression of cell surface functional molecules) were strictly controlled during inflammation process. This is one of the important mechanisms to retain the host homeostasis. |
| 资助项目 | National Natural Science Foundation of China[A30171086] ; Knowledge Innovation Program of Chinese Academy of Sciences[KSCX2-SW-202] |
| WOS研究方向 | Immunology |
| 语种 | 英语 |
| WOS记录号 | WOS:000208922100009 |
| 出版者 | CHIN SOCIETY IMMUNOLOGY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/274116]  |
| 专题 | 药理学第一研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Zou, Jianping |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Lab Immunopharmacol, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wu, Qingli,Feng, Yonghong,Yang, Yifu,et al. Kinetics of the Phenotype and Function of Murine Peritoneal Macrophages Following Acute Inflammation[J]. CELLULAR & MOLECULAR IMMUNOLOGY,2004,1(1):57-62. |
| APA | Wu, Qingli.,Feng, Yonghong.,Yang, Yifu.,Liu, Jing.,Zhou, Wenliang.,...&Zou, Jianping.(2004).Kinetics of the Phenotype and Function of Murine Peritoneal Macrophages Following Acute Inflammation.CELLULAR & MOLECULAR IMMUNOLOGY,1(1),57-62. |
| MLA | Wu, Qingli,et al."Kinetics of the Phenotype and Function of Murine Peritoneal Macrophages Following Acute Inflammation".CELLULAR & MOLECULAR IMMUNOLOGY 1.1(2004):57-62. |
入库方式： OAI收割
来源：上海药物研究所
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