Endogenous Bioactive Jasmonate Is Composed of a Set of (+)-7-iso-JA- Amino Acid Conjugates
文献类型：期刊论文
| 作者 | Yan, Jianbin1,2; Li, Suhua1,2; Gu, Min3 ; Yao, Ruifeng1,2; Li, Yuwen1,2; Chen, Juan1,2; Yang, Mai1,2; Tong, Jianhua4; Xiao, Langtao4; Nan, Fajun3
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| 刊名 | PLANT PHYSIOLOGY
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| 出版日期 | 2016-12 |
| 卷号 | 172期号:4页码:2154-2164 |
| ISSN号 | 0032-0889 |
| DOI | 10.1104/pp.16.00906 |
| 文献子类 | Article |
| 英文摘要 | Jasmonates (JAs) regulate a wide range of plant defense and development processes. The bioactive JA is perceived by its receptor COI1 to trigger the degradation of JASMONATE ZIM-DOMAIN (JAZ) proteins and subsequently derepress the JAZ-repressed transcription factors for activation of expression of JA-responsive genes. So far, (+)-7-iso-JA-L-Ile has been the only identified endogenous bioactive JA molecule. Here, we designed coronafacic acid (CFA) conjugates with all the amino acids (CFA-AA) to mimic the JA amino acid conjugates, and revealed that (+)-7-iso-JA-Leu, (+)-7-iso-JA-Val, (+)-7-iso-JA-Met, and (+)-7-iso-JA-Ala are new endogenous bioactive JA molecules. Furthermore, our studies uncover the general characteristics for all the bioactive JA molecules, and provide a new strategy to synthetically generate novel active JA molecules. |
| WOS关键词 | ANTHOCYANIN ACCUMULATION ; CORONATINE INSENSITIVE1 ; ARABIDOPSIS-THALIANA ; STRUCTURAL BASIS ; RECEPTOR ; BIOSYNTHESIS ; PROTEINS ; ISOLEUCINE ; MECHANISM ; DEFENSE |
| 资助项目 | Ministry of Science and Technology[2016YFA0500501] ; National Science Foundation of China[31421001] ; National Science Foundation of China[31230008] ; National Science Foundation of China[31570372] ; Natural Science Foundation of Shanghai[13ZR1410500] |
| WOS研究方向 | Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000391173400007 |
| 出版者 | AMER SOC PLANT BIOLOGISTS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275775]  |
| 专题 | 国家新药筛选中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yan, Jianbin; Nan, Fajun; Xie, Daoxin |
| 作者单位 | 1.Tsinghua Univ, Tsinghua Peking Joint Ctr Life Sci, Beijing 100084, Peoples R China; 2.Tsinghua Univ, Sch Life Sci, MOE Key Lab Bioinformat, Beijing 100084, Peoples R China; 3.Chinese Acad Sci, Natl Ctr Drug Screening, Shanghai Inst Mat Med, Shanghai Inst Biol Sci,State Key Lab Drug Res, Shanghai 201203, Peoples R China; 4.Hunan Agr Univ, Hunan Prov Key Lab Crop Germplasm Innovat & Utili, Hunan Prov Key Lab Phytohormones & Growth Dev, Changsha 410128, Hunan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yan, Jianbin,Li, Suhua,Gu, Min,et al. Endogenous Bioactive Jasmonate Is Composed of a Set of (+)-7-iso-JA- Amino Acid Conjugates[J]. PLANT PHYSIOLOGY,2016,172(4):2154-2164. |
| APA | Yan, Jianbin.,Li, Suhua.,Gu, Min.,Yao, Ruifeng.,Li, Yuwen.,...&Xie, Daoxin.(2016).Endogenous Bioactive Jasmonate Is Composed of a Set of (+)-7-iso-JA- Amino Acid Conjugates.PLANT PHYSIOLOGY,172(4),2154-2164. |
| MLA | Yan, Jianbin,et al."Endogenous Bioactive Jasmonate Is Composed of a Set of (+)-7-iso-JA- Amino Acid Conjugates".PLANT PHYSIOLOGY 172.4(2016):2154-2164. |
入库方式： OAI收割
来源：上海药物研究所
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