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Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors
文献类型：期刊论文
| 作者 | Sun, Huiping1,2,3; Su, Jinghan1,2; Meng, Qingshuo1,2; Yin, Qi1,2 ; Chen, Lingli1,2; Gu, Wangwen1,2; Zhang, Pengcheng1,2; Zhang, Zhiwen1,2; Yu, Haijun1,2; Wang, Siling3
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| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2016-11-16 |
| 卷号 | 28期号:43页码:9581-+ |
| ISSN号 | 0935-9648 |
| DOI | 10.1002/adma.201602173 |
| 文献子类 | Article |
| 英文摘要 | A unique biomimetic drug-delivery system composed of 4T1-breast-cancercell membranes and paclitaxel-loaded polymeric nanoparticles (PPNs) (cell-membrane-coated PPNs), demonstrates superior interactions to its source tumor cells and elongated blood circulation, and displays highly cell-specific targeting of the homotypic primary tumor and metastases, with successful inhibition of the growth and lung metastasis of the breast cancer cells. |
| WOS关键词 | BREAST-CANCER ; LUNG METASTASIS ; DRUG-DELIVERY ; AGGREGATION ; INHIBITION ; ANGIOGENESIS ; LIPOSOMES ; MEMBRANES ; GROWTH |
| 资助项目 | National Natural Science Foundation of China[81521005] ; National Natural Science Foundation of China[81270047] ; National Basic Research Program of China[2013CB932704] ; National Basic Research Program of China[2012CB932502] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000391175000018 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275806]  |
| 专题 | 药物制剂研究中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Wang, Siling; Li, Yaping |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, 501 Haike Rd, Shanghai 201203, Peoples R China; 3.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Huiping,Su, Jinghan,Meng, Qingshuo,et al. Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors[J]. ADVANCED MATERIALS,2016,28(43):9581-+. |
| APA | Sun, Huiping.,Su, Jinghan.,Meng, Qingshuo.,Yin, Qi.,Chen, Lingli.,...&Li, Yaping.(2016).Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors.ADVANCED MATERIALS,28(43),9581-+. |
| MLA | Sun, Huiping,et al."Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors".ADVANCED MATERIALS 28.43(2016):9581-+. |
入库方式： OAI收割
来源：上海药物研究所
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