Carbohydrate CuAAC click chemistry for therapy and diagnosis
文献类型：期刊论文
| 作者 | He, Xiao-Peng2,3; Zeng, Ya-Li2,3; Zang, Yi1 ; Li, Jia1; Field, Robert A.4; Chen, Guo-Rong2,3
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| 刊名 | CARBOHYDRATE RESEARCH
 |
| 出版日期 | 2016-06-24 |
| 卷号 | 429页码:1-22 |
| 关键词 | Click chemistry Carbohydrate CuAAC Therapy Diagnosis |
| ISSN号 | 0008-6215 |
| DOI | 10.1016/j.carres.2016.03.022 |
| 文献子类 | Review |
| 英文摘要 | Carbohydrates are important as signaling molecules and for cellular recognition events, therefore offering scope for the development of carbohydrate-mimetic diagnostics and drug candidates. As a consequence, the construction of carbohydrate-based bioactive compounds and sensors has become an active research area. While the advent of click chemistry has greatly accelerated the progress of medicinal chemistry and chemical biology, recent literature has seen an extensive use of such approaches to construct functionally diverse carbohydrate derivatives. Here we summarize some of the progress, covering the period 2010 to mid-2015, in Cu-I-catalyzed azide-alkyne 1,3-dipolar cycloaddition CuAAC "click chemistry" of carbohydrate derivatives, in the context of potential therapeutic and diagnostic tool development. (C) 2016 The Authors. Published by Elsevier Ltd. |
| WOS关键词 | AGGREGATION-INDUCED-EMISSION ; AERUGINOSA LECTIN LECA ; GLYCOGEN-PHOSPHORYLASE INHIBITORS ; TYROSINE-PHOSPHATASE INHIBITORS ; N-SUBSTITUTED AMINOCYCLITOLS ; GALACTOSYL CERAMIDE ANALOGS ; RING-OPENING POLYMERIZATION ; TRIAZOLE-LINKED GLYCOLIPIDS ; AZIDE-ALKYNE CYCLOADDITION ; ESCHERICHIA-COLI ADHESION |
| 资助项目 | 973 project[2013CB733700] ; National Natural Science Foundation of China[21572058] ; National Natural Science Foundation of China[21576088] ; Key Project of the Shanghai Science and Technology Commission[13NM1400900] ; Fundamental Research Funds for Central Universities[222201414010] ; UK BBSRC Institute Strategic Programme Grant on Understanding and Exploiting Metabolism (MET)[BB/J004561/1] ; John Innes Foundation[00000000] ; Biotechnology and Biological Sciences Research Council[BB/M021769/1] ; Biotechnology and Biological Sciences Research Council[BBS/E/J/000C0618] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000377289100001 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/275988]  |
| 专题 | 国家新药筛选中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物安全性评价中心 |
| 通讯作者 | Li, Jia; Field, Robert A.; Chen, Guo-Rong |
| 作者单位 | 1.Chinese Acad Sci, Natl Ctr Drug Screening, State Key Lab Drug Res, Shanghai Inst Mat Med, 189 Guo Shoujing Rd, Shanghai 201203, Peoples R China; 2.E China Univ Sci & Technol, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China; 3.E China Univ Sci & Technol, Inst Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China; 4.John Innes Ctr, Dept Biol Chem, Norwich Res Pk, Norwich NR4 7UH, Norfolk, England |
| 推荐引用方式 GB/T 7714 | He, Xiao-Peng,Zeng, Ya-Li,Zang, Yi,et al. Carbohydrate CuAAC click chemistry for therapy and diagnosis[J]. CARBOHYDRATE RESEARCH,2016,429:1-22. |
| APA | He, Xiao-Peng,Zeng, Ya-Li,Zang, Yi,Li, Jia,Field, Robert A.,&Chen, Guo-Rong.(2016).Carbohydrate CuAAC click chemistry for therapy and diagnosis.CARBOHYDRATE RESEARCH,429,1-22. |
| MLA | He, Xiao-Peng,et al."Carbohydrate CuAAC click chemistry for therapy and diagnosis".CARBOHYDRATE RESEARCH 429(2016):1-22. |
入库方式： OAI收割
来源：上海药物研究所
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