Rare Sesquiterpenoids from the Shed Trunk Barks of the Critically Endangered Plant Abies beshanzuensis and Their Bioactivities
文献类型：期刊论文
| 作者 | Hu, Chang-Ling2; Xiong, Juan2; Li, Ji-Yang3; Gao, Li-Xin1; Wang, Wen-Xuan2; Cheng, Ke-Jun4; Yang, Guo-Xun2; Li, Jia1 ; Hu, Jin-Feng2
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| 刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
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| 出版日期 | 2016-04 |
| 期号 | 10页码:1832-1835 |
| ISSN号 | 1434-193X |
| 关键词 | Natural products Terpenoids Beshanzuenones Biological activities Abies beshanzuensis |
| DOI | 10.1002/ejoc.201600165 |
| 文献子类 | Article |
| 英文摘要 | Two rare rearranged cuparane-type sesquiterpenoid C-10 epimers [beshanzuenones A (1) and B (2)] and two bisabolane-type sesquiterpenoid spirolactones [beshanzuenones C (3) and D (4)] featuring an unusual [6/6/5]-fused tricyclic ring system were isolated from the shed trunk barks of Abies beshanzuensis, one of the critically endangered plant species in the world. The structures of these four new enone-containing sesquiterpenoids were determined by spectroscopic analyses and single-crystal X-ray diffraction or electronic circular dichroism (ECD) calculations. Compounds 1 and 2 showed considerable activity against the H3N2 virus, whereas 3 and 4 exhibited significant inhibition on PTP1B. |
| WOS关键词 | DITERPENOIDS ; METABOLITES |
| 资助项目 | National Natural Science Foundation of China (NSFC)[21472021] ; National Natural Science Foundation of China (NSFC)[81273401] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000374148100005 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276089]  |
| 专题 | 国家新药筛选中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物安全性评价中心 |
| 通讯作者 | Hu, Jin-Feng |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.Fudan Univ, Sch Pharm, Dept Nat Prod Chem, Shanghai 201203, Peoples R China; 3.Fudan Univ, Sch Pharm, Dept Biosynth, Shanghai 201203, Peoples R China; 4.Lishui Inst Agr Sci, Chem Biol Ctr, Lishui 323000, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Chang-Ling,Xiong, Juan,Li, Ji-Yang,et al. Rare Sesquiterpenoids from the Shed Trunk Barks of the Critically Endangered Plant Abies beshanzuensis and Their Bioactivities[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2016(10):1832-1835. |
| APA | Hu, Chang-Ling.,Xiong, Juan.,Li, Ji-Yang.,Gao, Li-Xin.,Wang, Wen-Xuan.,...&Hu, Jin-Feng.(2016).Rare Sesquiterpenoids from the Shed Trunk Barks of the Critically Endangered Plant Abies beshanzuensis and Their Bioactivities.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(10),1832-1835. |
| MLA | Hu, Chang-Ling,et al."Rare Sesquiterpenoids from the Shed Trunk Barks of the Critically Endangered Plant Abies beshanzuensis and Their Bioactivities".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .10(2016):1832-1835. |
入库方式： OAI收割
来源：上海药物研究所
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