One-pot transition-metal-free cascade synthesis of thieno[2,3-c]coumarins from chromones
文献类型：期刊论文
| 作者 | Yang, Yuhong1,2; Qi, Xueyu1,2; Liu, Ruiling1,2; He, Qian1,2 ; Yang, Chunhao1,2
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:106页码:103895-103898 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c6ra21776a |
| 文献子类 | Article |
| 英文摘要 | A one-pot transition-metal-free, base-mediated synthesis of a novel series of functionalized thieno[2,3-c]coumarins via a cascade reaction from chromones has been developed. This cascade reaction involves a Michael addition-Knoevenagel condensation-intramolecular cyclization. This transformation proceeds under mild conditions and gives various thieno[ 2,3-c]coumarins in good-to-excellent yields. The methodology is tolerant of a wide range of functional groups and applicable to library synthesis. |
| WOS关键词 | ETHYL MERCAPTOACETATE ; COUMARIN DERIVATIVES ; EFFICIENT SYNTHESIS ; RECEPTOR ; AGENTS ; BENZOPYRANONES ; REARRANGEMENT ; INHIBITORS ; COUMESTROL ; CATALYSIS |
| 资助项目 | National Natural Science Foundation of China[81321092] ; SKLDR/SIMM[SIMM1601ZZ-03] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000388111900004 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276189]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yang, Chunhao |
| 作者单位 | 1.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Dept Med Chem, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Yang, Yuhong,Qi, Xueyu,Liu, Ruiling,et al. One-pot transition-metal-free cascade synthesis of thieno[2,3-c]coumarins from chromones[J]. RSC ADVANCES,2016,6(106):103895-103898. |
| APA | Yang, Yuhong,Qi, Xueyu,Liu, Ruiling,He, Qian,&Yang, Chunhao.(2016).One-pot transition-metal-free cascade synthesis of thieno[2,3-c]coumarins from chromones.RSC ADVANCES,6(106),103895-103898. |
| MLA | Yang, Yuhong,et al."One-pot transition-metal-free cascade synthesis of thieno[2,3-c]coumarins from chromones".RSC ADVANCES 6.106(2016):103895-103898. |
入库方式： OAI收割
来源：上海药物研究所
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