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Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment

文献类型：期刊论文

作者Zhang, Pengcheng1,2; Hu, Chunhua1,2,3; Ran, Wei1,2,4; Meng, Jia1,2,4; Yin, Qi1,2; Li, Yaping1,2
刊名THERANOSTICS
出版日期2016
卷号6期号:7页码:948-968
关键词Nanoparticle theranostics imaging photodynamic photothermal
ISSN号1838-7640
DOI10.7150/thno.15217
文献子类Review
英文摘要Treatments of high specificity are desirable for cancer therapy. Light-triggered nanotheranostics (LTN) mediated cancer therapy could be one such treatment, as they make it possible to visualize and treat the tumor specifically in a light-controlled manner with a single injection. Because of their great potential in cancer therapy, many novel and powerful LTNs have been developed, and are mainly prepared from photosensitizers (PSs) ranging from small organic dyes such as porphyrin-and cyanine-based dyes, semiconducting polymers, to inorganic nanomaterials such as gold nanoparticles, transition metal chalcogenides, carbon nanotubes and graphene. Using LTNs and localized irradiation in combination, complete tumor ablation could be achieved in tumor-bearing animal models without causing significant toxicity. Given their great advances and promising future, we herein review LTNs that have been tested in vivo with a highlight on progress that has been made in the past a couple of years. The current challenges faced by these LTNs are also briefly discussed.
WOS关键词GUIDED PHOTOTHERMAL THERAPY ; NEAR-INFRARED LIGHT ; COPPER SULFIDE NANOPARTICLES ; UP-CONVERSION NANOPARTICLES ; WALLED CARBON NANOTUBES ; REDUCED GRAPHENE OXIDE ; TARGETED PHOTODYNAMIC THERAPY ; AGGREGATION-INDUCED EMISSION ; GOLD NANOROD VESICLES ; HUMAN SERUM-ALBUMIN
资助项目National Natural Science Foundation of China[81521005] ; National Natural Science Foundation of China[81270047] ; National Basic Research Program of China[2012CB932502] ; National Basic Research Program of China[2013CB932503] ; Shanghai Pujiang Program[15PJ1409900]
WOS研究方向Research & Experimental Medicine
语种英语
WOS记录号WOS:000377799600004
出版者IVYSPRING INT PUBL
源URL[http://119.78.100.183/handle/2S10ELR8/276225]  
专题药物制剂研究中心
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Li, Yaping
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, 501 Haike Rd, Shanghai 201203, Peoples R China;
3.Univ Sci & Technol China, Nano Sci & Technol Inst, Suzhou 215123, Peoples R China;
4.UCAS, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Pengcheng,Hu, Chunhua,Ran, Wei,et al. Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment[J]. THERANOSTICS,2016,6(7):948-968.
APA Zhang, Pengcheng,Hu, Chunhua,Ran, Wei,Meng, Jia,Yin, Qi,&Li, Yaping.(2016).Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment.THERANOSTICS,6(7),948-968.
MLA Zhang, Pengcheng,et al."Recent Progress in Light-Triggered Nanotheranostics for Cancer Treatment".THERANOSTICS 6.7(2016):948-968.

入库方式： OAI收割

来源：上海药物研究所

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