Development of artemisinin drugs in the treatment of autoimmune diseases
文献类型：期刊论文
| 作者 | Wu, Yanwei; Tang, Wei ; Zuo, Jianping
|
| 刊名 | SCIENCE BULLETIN
 |
| 出版日期 | 2016-01 |
| 卷号 | 61期号:1页码:37-41 |
| 关键词 | Artemisinin Autoimmune disease Anti-inflammatory Immunosuppressive SM934 |
| ISSN号 | 2095-9273 |
| DOI | 10.1007/s11434-015-0975-9 |
| 文献子类 | Review |
| 英文摘要 | Artemisinin drugs are a family of sesquiterpene trioxane lactone agents originally derived from Artemisia annua L. Due to the big victory in the antimalarial battle, the 2015 Nobel Prize goes to the discoverer of artemisinin-based therapy for malaria. Beyond antimalaria, artemisinin and its derivatives are also being investigated in diseases like schistosomiasis, viral infection, cancers and inflammation. Over the past decades, the anti-inflammatory and immunomodulatory effects of artemisinin drugs have been comprehensively studied. In this article, we will briefly describe the development of artemisinin drugs, especially novel artemisinin derivatives, in the treatment of autoimmune diseases. |
| WOS关键词 | EXPERIMENTAL RHEUMATOID-ARTHRITIS ; IMMUNOSUPPRESSIVE ACTIVITY ; SIGNALING PATHWAY ; DERIVATIVE SM905 ; MRL/LPR MICE ; ARTESUNATE ; DIHYDROARTEMISININ ; RESPONSES ; ACTIVATION ; EXPRESSION |
| 资助项目 | Natural Science Foundation of China[8127352] ; Natural Science Foundation of China[81273525] ; Natural Science Foundation of China[81322049] ; National Key Basic Research Programme[2014CB541906] |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5629035 |
| WOS记录号 | WOS:000369368400005 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276253]  |
| 专题 | 药理学第一研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Tang, Wei; Zuo, Jianping |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Lab Immunopharmacol, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Yanwei,Tang, Wei,Zuo, Jianping. Development of artemisinin drugs in the treatment of autoimmune diseases[J]. SCIENCE BULLETIN,2016,61(1):37-41. |
| APA | Wu, Yanwei,Tang, Wei,&Zuo, Jianping.(2016).Development of artemisinin drugs in the treatment of autoimmune diseases.SCIENCE BULLETIN,61(1),37-41. |
| MLA | Wu, Yanwei,et al."Development of artemisinin drugs in the treatment of autoimmune diseases".SCIENCE BULLETIN 61.1(2016):37-41. |
入库方式： OAI收割
来源：上海药物研究所
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