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  4. 天然药物化学研究室
Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc

文献类型：期刊论文

作者Zhang, Panpan1,2,3; Tang, Chunping1,2,4,5; Yao, Sheng1,2,4,5; Ke, Changqiang1,2,4,5; Lin, Ge4,5,6; Hua, Hui-Ming3; Ye, Yang1,2,4,5,7
刊名JOURNAL OF NATURAL PRODUCTS
出版日期2016-01
卷号79期号:1页码:24-29
ISSN号0163-3864
DOI10.1021/acs.jnatprod.5b00520
文献子类Article
英文摘要Ten new cassane-type diterpenoids, caesalbonducins DF (13), 6-deacetoxybonducellpin B (4), 3-acetoxy-alpha-caesalpin (5), 2(3)-en-alpha-caesalpin (6), 1 alpha-hydroxycaesalpinin J (7), 1 alpha-hydroxy-6-decaetoxysalpinin J (8), 6 alpha-hydroxycaesall M (9), and 6 alpha-hydroxy-14(17)-dehydrocaesalpin F (10), along with eight known compounds (1118), were isolated from the pericarps of Caesalpinia bonduc. Compounds 13 and 11 are methyl-migrated cassane-type diterpenoids with a 19(4 -> 3)-cassane skeleton. The structures of 110 were elucidated on the basis of 1D and 2D NMR methods and other spectroscopic analysis. The neuroprotective effects of the isolated compounds were evaluated.
WOS关键词SEED KERNELS ; CRISTA ; FURANODITERPENES
资助项目National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program"[2012ZX09301001-001] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program"[2015ZX09103002] ; National Natural Science Funds of China[81302657] ; National Natural Science Funds of China[81573305] ; National Natural Science Funds of China[81473112] ; Ministry of Science and Technology[2010DFA30980] ; Chinese Academy of Sciences[KSZD-EW-Z-004-01] ; Shanghai Commission of Science and Technology[11DZ1970700] ; Shanghai Commission of Science and Technology[12JC1410300]
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000368755000004
出版者AMER CHEMICAL SOC
源URL[http://119.78.100.183/handle/2S10ELR8/276254]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Hua, Hui-Ming; Ye, Yang
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Mat Med, Nat Prod Chem Dept, 555 Zu Chong Zhi Rd,Zhangjiang Hi Tech Pk, Shanghai 201203, Peoples R China;
3.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China;
4.Chinese Acad Sci, Shanghai Inst Mat Med, Joint Res Lab Promoting Globalizat Tradit Chines, Hong Kong, Hong Kong, Peoples R China;
5.Chinese Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China;
6.Chinese Univ Hong Kong, Fac Med, Sch Biomed Sci, Hong Kong, Hong Kong, Peoples R China;
7.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Panpan,Tang, Chunping,Yao, Sheng,et al. Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc[J]. JOURNAL OF NATURAL PRODUCTS,2016,79(1):24-29.
APA Zhang, Panpan.,Tang, Chunping.,Yao, Sheng.,Ke, Changqiang.,Lin, Ge.,...&Ye, Yang.(2016).Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc.JOURNAL OF NATURAL PRODUCTS,79(1),24-29.
MLA Zhang, Panpan,et al."Cassane Diterpenoids from the Pericarps of Caesalpinia bonduc".JOURNAL OF NATURAL PRODUCTS 79.1(2016):24-29.

入库方式： OAI收割

来源：上海药物研究所

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