TCM, brain function and drug space
文献类型：期刊论文
| 作者 | Tang, Chunping1,2,3 ; Ye, Yang2,3; Feng, Yunjiang1,3; Quinn, Ronald J.1,3
|
| 刊名 | NATURAL PRODUCT REPORTS
 |
| 出版日期 | 2016-01 |
| 卷号 | 33期号:1页码:6-25 |
| ISSN号 | 0265-0568 |
| DOI | 10.1039/c5np00049a |
| 文献子类 | Review |
| 英文摘要 | Traditional Chinese medicine has played a significant rote in the mainstream healthcare system in China for thousands of years. Here, we summarize 84 major compounds from 15 selected herbal medicines targeting neurodegenerative diseases. We present a perspective based on the analysis of physicochemical properties of these TCM compounds, and comparison with current drugs and candidates for the treatment of Parkinson's and Alzheimer's disease. The results demonstrate that traditional Chinese medicines contain compounds possessing physicochemical properties that have excellent overlap with developed western medicines. |
| WOS关键词 | GLUTAMATE-INDUCED APOPTOSIS ; INDUCED OXIDATIVE STRESS ; CENTRAL-NERVOUS-SYSTEM ; NEURON-GLIA CULTURES ; PROTECTS PC12 CELLS ; SALVIA-MILTIORRHIZA ; RAT-BRAIN ; 3,6'-DISINAPOYL SUCROSE ; CARDIOVASCULAR-DISEASES ; LIQUID-CHROMATOGRAPHY |
| 资助项目 | Griffith University International Postgraduate Research Scholarship (GUIPRS)[00000000] ; Griffith University Postgraduate Research Scholarship (GUPRS)[00000000] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program" in China[2012ZX09301001-001] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000368755100001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276256]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Quinn, Ronald J. |
| 作者单位 | 1.Griffith Univ, Eskitis Inst Drug Discovery, Brisbane, Qld 4111, Australia; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Eskitis SIMM Joint Lab Drug Discovery, Brisbane, Qld, Australia |
| 推荐引用方式 GB/T 7714 | Tang, Chunping,Ye, Yang,Feng, Yunjiang,et al. TCM, brain function and drug space[J]. NATURAL PRODUCT REPORTS,2016,33(1):6-25. |
| APA | Tang, Chunping,Ye, Yang,Feng, Yunjiang,&Quinn, Ronald J..(2016).TCM, brain function and drug space.NATURAL PRODUCT REPORTS,33(1),6-25. |
| MLA | Tang, Chunping,et al."TCM, brain function and drug space".NATURAL PRODUCT REPORTS 33.1(2016):6-25. |
入库方式： OAI收割
来源：上海药物研究所
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