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Activatable nanoprobes for biomolecular detection

文献类型：期刊论文

作者Zhang, Pengcheng2; Cheetham, Andrew. G.2; Lock, Lye Lin2; Li, Yaping3,4; Cui, Honggang1,2,5
刊名CURRENT OPINION IN BIOTECHNOLOGY
出版日期2015-08
卷号34页码:171-179
ISSN号0958-1669
DOI10.1016/j.copbio.2015.01.009
文献子类Review
英文摘要Precise detection of pathologically relevant biomolecules could provide essential information on important intercellular, cellular, and subcellular events for accurate disease diagnosis and staging, thus leading to appropriate treatment recommendation. Activatable nanoprobes are nanoscale objects that can be turned on through specific reactions or interactions with biomolecules of interest, and afford some advantageous properties for improved detection of biomolecules both in vitro and in vivo. In this brief review, we highlight several recent examples in the development of activatable nanoprobes for biomolecule detection.
WOS关键词CELL-PENETRATING PEPTIDES ; IN-VIVO ; HYDROGEN-PEROXIDE ; PROTEASE ACTIVITY ; CONTRAST AGENTS ; SMALL MOLECULES ; LIVE CELLS ; CANCER ; NANOPARTICLES ; FLUORESCENCE
资助项目W.W. Smith Charitable Trust[00000000]
WOS研究方向Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology
语种英语
WOS记录号WOS:000361256300024
出版者CURRENT BIOLOGY LTD
源URL[http://119.78.100.183/handle/2S10ELR8/276444]  
专题药物制剂研究中心
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Cui, Honggang
作者单位1.Johns Hopkins Univ, Sch Med, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21205 USA
2.Johns Hopkins Univ, Inst NanoBioTechnol, Dept Chem & Biomol Engn, Baltimore, MD 21218 USA;
3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China;
4.Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China;
5.Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA;
推荐引用方式
GB/T 7714		 Zhang, Pengcheng,Cheetham, Andrew. G.,Lock, Lye Lin,et al. Activatable nanoprobes for biomolecular detection[J]. CURRENT OPINION IN BIOTECHNOLOGY,2015,34:171-179.
APA Zhang, Pengcheng,Cheetham, Andrew. G.,Lock, Lye Lin,Li, Yaping,&Cui, Honggang.(2015).Activatable nanoprobes for biomolecular detection.CURRENT OPINION IN BIOTECHNOLOGY,34,171-179.
MLA Zhang, Pengcheng,et al."Activatable nanoprobes for biomolecular detection".CURRENT OPINION IN BIOTECHNOLOGY 34(2015):171-179.

入库方式： OAI收割

来源：上海药物研究所

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