A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells
文献类型：期刊论文
| 作者 | Zhang, Xuan1 ; Zhang, Lun2; Liu, Yaqian1; Bao, Bin1; Zang, Yi2; Li, Jia2; Lu, Wei1
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2015-07-22 |
| 卷号 | 71期号:29页码:4842-4845 |
| 关键词 | Probe Hydrogen peroxide Near-infrared ROS |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2015.05.025 |
| 文献子类 | Article |
| 英文摘要 | A new near-infrared and colorimetric fluorescent molecular probe was developed for rapid detection of H2O2. The near-infrared fluorescence OFF ON switch is triggered by transformation of phenylboronic acid unit to phenol in the presence of H2O2. No quinone methides are released in this process, which is preferable for in vivo studies. In addition, probe 1 at low concentration exhibits high quality optical imaging during a short period in in vitro cell study. (C) 2015 Elsevier Ltd. All rights reserved. |
| WOS关键词 | MITOCHONDRIAL-DNA MUTATIONS ; REACTIVE OXYGEN ; OXIDATIVE STRESS ; IN-VIVO ; DISEASE ; CANCER ; GLUTATHIONE ; MECHANISMS ; SULFIDE ; SYSTEMS |
| 资助项目 | National Natural Science Foundation of China[81172936] ; National Natural Science Foundation of China[91213303] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000357348100020 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276465]  |
| 专题 | 国家新药筛选中心 中国科学院上海药物研究所 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物安全性评价中心 |
| 通讯作者 | Li, Jia |
| 作者单位 | 1.E China Normal Univ, Sch Chem & Mol Engn, Shanghai 200062, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xuan,Zhang, Lun,Liu, Yaqian,et al. A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells[J]. TETRAHEDRON,2015,71(29):4842-4845. |
| APA | Zhang, Xuan.,Zhang, Lun.,Liu, Yaqian.,Bao, Bin.,Zang, Yi.,...&Lu, Wei.(2015).A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells.TETRAHEDRON,71(29),4842-4845. |
| MLA | Zhang, Xuan,et al."A near-infrared fluorescent probe for rapid detection of hydrogen peroxide in living cells".TETRAHEDRON 71.29(2015):4842-4845. |
入库方式： OAI收割
来源：上海药物研究所
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