Lysophospholipids from the Guangxi Sponge Spirastrella purpurea
文献类型：期刊论文
| 作者 | Lin, Kun1; Yang, Peng1; Yang, Hui1; Liu, Ai-Hong2; Yao, Li-Gong3; Guo, Yue-Wei3 ; Mao, Shui-Chun1
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| 刊名 | LIPIDS
 |
| 出版日期 | 2015-07 |
| 卷号 | 50期号:7页码:697-703 |
| 关键词 | Sponge Spirastrella purpurea Marine natural products Lysophospholipids Guangxi Antifungal activity Neuroprotective activity HPLC NMR |
| ISSN号 | 0024-4201 |
| DOI | 10.1007/s11745-015-4028-6 |
| 文献子类 | Article |
| 英文摘要 | Four known (1-4) and two new (5 and 6) lysophospholipids were isolated from the sponge Spirastrella purpurea from Weizhou Island, Guangxi Autonomous Region, China. The structures of the new compounds (5 and 6) were elucidated by detailed spectroscopic techniques, including 1D and 2D NMR (H-1 and C-13 NMR, H-1-H-1 COSY, HSQC, and HMBC) as well as mass spectrometry and optical rotation experiments. The known compounds (1-4) were identified by comparison of their spectroscopic data and specific optical rotation with those reported in the literature. The isolated compounds displayed various moderate in vitro antifungal activities against four fungi (Cryptococcus neoformans, Candida glabrata, Trichophyton rubrum, and Aspergillus fumigatus), whereas they displayed no neuroprotective activity against A beta(25-35)-induced SH-SY5Y cell damage. |
| WOS关键词 | PLATELET-ACTIVATING-FACTOR ; ALGA CAULERPA-RACEMOSA ; ETHER PHOSPHOLIPIDS ; GUINEA-PIG ; LYSOPHOSPHATIDYLCHOLINES ; DERIVATIVES ; ARTHROPODS ; INHIBITORS ; INCONSTANS ; CELLS |
| 资助项目 | National Natural Science Foundation of China[81001397] ; National Natural Science Foundation of China[21162016] ; National Natural Science Foundation of China[21362024] ; Young Scientists Training Program of Jiangxi Province[20133BCB23004] ; Natural Science Foundation of Jiangxi Province[20114BAB205034] ; Foundation of Education Department of Jiangxi Province[GJJ12028] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Nutrition & Dietetics |
| 语种 | 英语 |
| WOS记录号 | WOS:000357280200009 |
| 出版者 | SPRINGER HEIDELBERG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276483]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Mao, Shui-Chun |
| 作者单位 | 1.Nanchang Univ, Sch Pharm, Nanchang 330006, Peoples R China; 2.Nanchang Univ, Ctr Anal & Testing, Nanchang 330047, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, Kun,Yang, Peng,Yang, Hui,et al. Lysophospholipids from the Guangxi Sponge Spirastrella purpurea[J]. LIPIDS,2015,50(7):697-703. |
| APA | Lin, Kun.,Yang, Peng.,Yang, Hui.,Liu, Ai-Hong.,Yao, Li-Gong.,...&Mao, Shui-Chun.(2015).Lysophospholipids from the Guangxi Sponge Spirastrella purpurea.LIPIDS,50(7),697-703. |
| MLA | Lin, Kun,et al."Lysophospholipids from the Guangxi Sponge Spirastrella purpurea".LIPIDS 50.7(2015):697-703. |
入库方式： OAI收割
来源：上海药物研究所
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