Synthesis of Rigid Analogues of Flavone by Intramolecular Heck Reaction
文献类型：期刊论文
| 作者 | Hou, Chuanwei1,2; Chen, Hao1; Xu, Xing1; Zhu, Fangxia1; Guo, Lei1; Jiang, Min1; Yang, Chunhao2 ; Deng, Lianfu1
|
| 刊名 | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2015-05 |
| 期号 | 14页码:3040-3043 |
| 关键词 | Flavone Heck reaction Synthetic methods Cross-coupling Palladium |
| ISSN号 | 1434-193X |
| DOI | 10.1002/ejoc.201500180 |
| 文献子类 | Article |
| 英文摘要 | A novel concise method to synthesize rigid analogues of flavone by an intramolecular Heck reaction with wide substrate scope was developed. The key intermediates 3-(2-bromo-benzyl)-4H-chromen-4-ones were prepared easily in two steps. Most compounds were obtained with moderate to good yields (34-90% yield, 19 examples). |
| WOS关键词 | IN-VITRO ; BENZODIAZEPINE-RECEPTOR ; OSTEOCLASTOGENESIS ; CHROMONE ; VIVO ; INHIBITION ; CHEMISTRY ; MECHANISM ; SCAFFOLD ; LIGANDS |
| 资助项目 | Shanghai Municipal Health Bureau young scientific research project[20144Y0055] ; Shanghai Committee of Science and Technology, China[13431900702] ; National Natural Science Foundation of China (NSFC)[81371958] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000354212000007 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276547]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Jiang, Min |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Shanghai Inst Traumatol & Orthopaed, Shanghai Ruijin Hosp, Shanghai Key Lab Bone & Joint Dis,Sch Med, Shanghai 20025, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hou, Chuanwei,Chen, Hao,Xu, Xing,et al. Synthesis of Rigid Analogues of Flavone by Intramolecular Heck Reaction[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2015(14):3040-3043. |
| APA | Hou, Chuanwei.,Chen, Hao.,Xu, Xing.,Zhu, Fangxia.,Guo, Lei.,...&Deng, Lianfu.(2015).Synthesis of Rigid Analogues of Flavone by Intramolecular Heck Reaction.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(14),3040-3043. |
| MLA | Hou, Chuanwei,et al."Synthesis of Rigid Analogues of Flavone by Intramolecular Heck Reaction".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .14(2015):3040-3043. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。