Multidrug resistance-reversal effects of resin glycosides from Dichondra repens
文献类型：期刊论文
| 作者 | Song, Wei-bin; Wang, Wen-qiong; Zhang, Shu-wei; Xuan, Li-jiang
|
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2015-02-15 |
| 卷号 | 25期号:4页码:795-798 |
| 关键词 | Dichondra repens Resin glycoside acids Multidrug-resistance (MDR) reversal activity |
| ISSN号 | 0960-894X |
| DOI | 10.1016/j.bmcl.2014.12.083 |
| 文献子类 | Article |
| 英文摘要 | Investigation of hydrophobic extract of Dichondra repens (Convolvulaceae) led to the isolation of three new resin glycosides dichondrins A-C (1-3), and three known resin glycosides cus-1, cus-2, and cuse 3. All the isolated resin glycosides with an acyclic core were evaluated for their multidrug resistance reversal activities, and the combined use of these compounds at a concentration of 25 mu M increased the cytotoxicity of vincristine by 1.03-1.78-fold. (C) 2015 The Authors. Published by Elsevier Ltd. |
| WOS关键词 | CUSCUTA-CHINENSIS ; SEEDS |
| 资助项目 | National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program', China[2009ZX09301-001] ; National Natural Sciences Foundation of China[81473111] ; China Postdoctoral Science Foundation[Y412021031] |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000349720400011 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276639]  |
| 专题 | 上海中药现代化研究中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Xuan, Li-jiang |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Wei-bin,Wang, Wen-qiong,Zhang, Shu-wei,et al. Multidrug resistance-reversal effects of resin glycosides from Dichondra repens[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2015,25(4):795-798. |
| APA | Song, Wei-bin,Wang, Wen-qiong,Zhang, Shu-wei,&Xuan, Li-jiang.(2015).Multidrug resistance-reversal effects of resin glycosides from Dichondra repens.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,25(4),795-798. |
| MLA | Song, Wei-bin,et al."Multidrug resistance-reversal effects of resin glycosides from Dichondra repens".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 25.4(2015):795-798. |
入库方式： OAI收割
来源：上海药物研究所
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