Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives
文献类型：期刊论文
| 作者 | Jiang, Min1; Xiang, Haoyue2; Zhu, Fangxia1; Xu, Xing1; Deng, Lianfu1; Yang, Chunhao2
|
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2015 |
| 卷号 | 13期号:40页码:10122-10126 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c5ob01642h |
| 文献子类 | Article |
| 英文摘要 | An efficient and practical one-pot domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives from readily available 2-(2-bromophenyl)acetonitriles was developed. The overall protocol involves a Buchwald-Hartwig type coupling and a base-promoted intramolecular nucleophilic reaction. The reaction scope, advantages and limitations are discussed. |
| WOS关键词 | ONE-POT SYNTHESIS ; ACCESS ; INDOLE ; ALPHA ; INDOLMYCIN ; INHIBITORS ; CHEMISTRY ; ARYLATION ; DIVERSE ; ANALOGS |
| 资助项目 | Shanghai Municipal Health Bureau young scientific research project[20144Y0055] ; Shanghai Committee of Science and Technology, China[14ZR1437500] ; Shanghai Committee of Science and Technology, China[13431900702] ; NSFC[81502902] ; NSFC[81321092] ; SKLDR/SIMM[SIMM1403ZZ-01] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000362729600005 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276702]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Deng, Lianfu |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Sch Med, Shanghai Ruijin Hosp, Shanghai Inst Traumatol & Orthopaed,Shanghai Key, Shanghai 200025, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Min,Xiang, Haoyue,Zhu, Fangxia,et al. Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2015,13(40):10122-10126. |
| APA | Jiang, Min,Xiang, Haoyue,Zhu, Fangxia,Xu, Xing,Deng, Lianfu,&Yang, Chunhao.(2015).Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives.ORGANIC & BIOMOLECULAR CHEMISTRY,13(40),10122-10126. |
| MLA | Jiang, Min,et al."Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives".ORGANIC & BIOMOLECULAR CHEMISTRY 13.40(2015):10122-10126. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。