An efficient and practical approach to trifluoromethylthiolation of alpha-haloketones/alpha-haloarylmethanes
文献类型：期刊论文
| 作者 | Jiang, Min1; Zhu, Fangxia1; Xiang, Haoyue2; Xu, Xing1; Deng, Lianfu1; Yang, Chunhao2
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| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2015 |
| 卷号 | 13期号:25页码:6935-6939 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c5ob00858a |
| 文献子类 | Article |
| 英文摘要 | An efficient and practical approach to trifluoromethylthiolation of alpha-haloketones/alpha-haloarylmethanes was developed. The transformation employs only AgSCF3 and KI in situ generated active nucleophilic trifluoromethylthio species and cleanly occurs in up to quantitative yield at room temperature, thereby providing an unprecedentedly easy entry to various alpha-SCF3-substituted ketones/arylmethanes. |
| WOS关键词 | COPPER-CATALYZED TRIFLUOROMETHYLTHIOLATION ; SILYL ENOL ETHERS ; C-H BONDS ; CARBONYL-COMPOUNDS ; OXIDATIVE TRIFLUOROMETHYLTHIOLATION ; MEDIATED TRIFLUOROMETHYLTHIOLATION ; SUBSTITUENT CONSTANTS ; ROOM-TEMPERATURE ; ELEMENTAL SULFUR ; BORONIC ACIDS |
| 资助项目 | Shanghai Municipal Health Bureau young scientific research project[20144Y0055] ; Shanghai Committee of Science and Technology, China[14ZR1437500] ; Shanghai Committee of Science and Technology, China[13431900702] ; NSFC[81371958] ; NSFC[81321092] ; SKLDR/SIMM[SIMM1403ZZ-01] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000356374500006 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276724]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Deng, Lianfu |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Shanghai Key Lab Bone & Joint Dis, Shanghai Inst Traumatol & Orthopaed, Shanghai Ruijin Hosp,Sch Med, Shanghai 20025, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Min,Zhu, Fangxia,Xiang, Haoyue,et al. An efficient and practical approach to trifluoromethylthiolation of alpha-haloketones/alpha-haloarylmethanes[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2015,13(25):6935-6939. |
| APA | Jiang, Min,Zhu, Fangxia,Xiang, Haoyue,Xu, Xing,Deng, Lianfu,&Yang, Chunhao.(2015).An efficient and practical approach to trifluoromethylthiolation of alpha-haloketones/alpha-haloarylmethanes.ORGANIC & BIOMOLECULAR CHEMISTRY,13(25),6935-6939. |
| MLA | Jiang, Min,et al."An efficient and practical approach to trifluoromethylthiolation of alpha-haloketones/alpha-haloarylmethanes".ORGANIC & BIOMOLECULAR CHEMISTRY 13.25(2015):6935-6939. |
入库方式： OAI收割
来源：上海药物研究所
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