Direct Synthesis of Diverse 2-Aminobenzo[b]thiophenes via Palladium-Catalyzed Carbon-Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source
文献类型：期刊论文
| 作者 | Hou, Chuanwei; He, Qian ; Yang, Chunhao
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2014-10-03 |
| 卷号 | 16期号:19页码:5040-5043 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol502381e |
| 文献子类 | Article |
| 英文摘要 | A novel and direct synthesis of various 2-aminobenzo[b]thiophenes has been developed. The reactions were catalyzed by a combination of Pd(dppf)Cl-2 and dppf using odorless and cheap Na2S2O3 as the sulfur source. This strategy allowed us to synthesize important 2-aminobenzo[b]thiophene scaffold more efficiently and conveniently. |
| WOS关键词 | ESTROGEN-RECEPTOR MODULATORS ; BIOLOGICAL EVALUATION ; ANTIMITOTIC AGENTS ; DERIVATIVES ; INHIBITORS ; RALOXIFENE ; SULFIDE ; REAGENT ; ACCESS ; ALPHA |
| 资助项目 | Ministry of Science and Technology of China[2012ZX09301001-001] ; National Natural Science Foundation of China[81321092] ; SKLDR/SIMM[SIMM1403ZZ-01] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000342719500019 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276874]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yang, Chunhao |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hou, Chuanwei,He, Qian,Yang, Chunhao. Direct Synthesis of Diverse 2-Aminobenzo[b]thiophenes via Palladium-Catalyzed Carbon-Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source[J]. ORGANIC LETTERS,2014,16(19):5040-5043. |
| APA | Hou, Chuanwei,He, Qian,&Yang, Chunhao.(2014).Direct Synthesis of Diverse 2-Aminobenzo[b]thiophenes via Palladium-Catalyzed Carbon-Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source.ORGANIC LETTERS,16(19),5040-5043. |
| MLA | Hou, Chuanwei,et al."Direct Synthesis of Diverse 2-Aminobenzo[b]thiophenes via Palladium-Catalyzed Carbon-Sulfur Bond Formation Using Na2S2O3 as the Sulfur Source".ORGANIC LETTERS 16.19(2014):5040-5043. |
入库方式： OAI收割
来源：上海药物研究所
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