Adenosylmethionine Decarboxylase 1 (AMD1)-Mediated mRNA Processing and Cell Adhesion Activated & Inhibited Transition Mechanisms by Different Comparisons Between Chimpanzee and Human Left Hemisphere
文献类型：期刊论文
| 作者 | Wang, Lin1,2; Huang, Juxiang1; Jiang, Minghu3; Diao, Haizhen1; Zhou, Huilei1; Li, Xiaohe1; Chen, Qingchun1; Jiang, Zhenfu4; Feng, Haitao5 |
| 刊名 | CELL BIOCHEMISTRY AND BIOPHYSICS
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| 出版日期 | 2014-09 |
| 卷号 | 70期号:1页码:279-288 |
| 关键词 | mRNA processing Cell adhesion Adenosylmethionine decarboxylase 1 (AMD1) Human left hemisphere Chimpanzee left hemisphere |
| ISSN号 | 1085-9195 |
| DOI | 10.1007/s12013-014-9902-y |
| 文献子类 | Article |
| 英文摘要 | To understand adenosylmethionine decarboxylase 1 (AMD1)-mediated mRNA processing and cell adhesion activated & inhibited transition mechanisms between chimpanzee and human left hemisphere, AMD1-activated different complete (all no positive correlation, Pearson correlation coefficient < 0.25) and uncomplete (partly no positive correlation except AMD1, Pearson < 0.25) networks were identified in higher human compared with lower chimpanzee left hemisphere from the corresponding AMD1-stimulated (Pearson a parts per thousand yen 0.25) or inhibited (Pearson a parts per thousand currency sign -0.25) overlapping molecules of Pearson and GRNInfer, respectively. This result was verified by the corresponding scatter matrix. As visualized by GO, KEGG, GenMAPP, BioCarta, and disease database integration, we proposed mainly that AMD1-stimulated different complete network was involved in AMD1 activation with cytoplasm ubiquitin specific peptidase (tRNA-guanine transglycosylase) to nucleus paired box-induced mRNA processing, whereas the corresponding inhibited network participated in AMD1 repression with cytoplasm protocadherin gamma and adaptor-related protein complex 3-induced cell adhesion in lower chimpanzee left hemisphere. However, AMD1-stimulated network contained AMD1 activation with plakophilin and phosphodiesterase to SH3 binding glutamic acid-rich protein to dynein and zinc finger-induced cell adhesion, whereas the corresponding inhibited different complete network included AMD1 repression with mitochondrial denine nucleotide translocator, brain protein, and ADH dehydrogenase to ribonucleoprotein-induced mRNA processing in higher human left hemisphere. Our AMD1 different networks were verified by AMD1-activated or -inhibited complete and uncomplete networks within and between chimpanzee left hemisphere or (and) human left hemisphere. |
| WOS关键词 | SYSTEMS-THEORETICAL ANALYSIS ; CYCLE COMPUTATIONAL NETWORK ; HEPATOCELLULAR-CARCINOMA ; TRISTETRAPROLIN ; PROTEIN ; SIGNAL ; HEPATITIS/CIRRHOSIS ; TRANSFORMATION ; CONSTRUCTION ; TISSUES |
| 资助项目 | National Natural Science Foundation of China[61171114] ; State Key Laboratory of Drug Research[SIMM1302KF] ; Automatical Scientific Planning of Tsinghua University[20111081023] ; Automatical Scientific Planning of Tsinghua University[20111081010] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics ; Cell Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000340593200040 |
| 出版者 | HUMANA PRESS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276931]  |
| 专题 | 新药研究国家重点实验室 中科院受体结构与功能重点实验室 |
| 通讯作者 | Wang, Lin |
| 作者单位 | 1.Beijing Univ Posts & Telecommun, Sch Elect Engn, Bioinformat Ctr, Beijing 100876, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State key Lab Drug Res, Shanghai 201203, Peoples R China; 3.Tsinghua Univ, Sch Humanities & Social Sci, Lab Computat Linguist, Beijing 100084, Peoples R China; 4.China Univ Min Technol, Sch Mech Elect Informat Engn, Beijing 100083, Peoples R China; 5.Heilongjiang Univ Chinese Med, Dean Dept, Harbin 150040, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Lin,Huang, Juxiang,Jiang, Minghu,et al. Adenosylmethionine Decarboxylase 1 (AMD1)-Mediated mRNA Processing and Cell Adhesion Activated & Inhibited Transition Mechanisms by Different Comparisons Between Chimpanzee and Human Left Hemisphere[J]. CELL BIOCHEMISTRY AND BIOPHYSICS,2014,70(1):279-288. |
| APA | Wang, Lin.,Huang, Juxiang.,Jiang, Minghu.,Diao, Haizhen.,Zhou, Huilei.,...&Feng, Haitao.(2014).Adenosylmethionine Decarboxylase 1 (AMD1)-Mediated mRNA Processing and Cell Adhesion Activated & Inhibited Transition Mechanisms by Different Comparisons Between Chimpanzee and Human Left Hemisphere.CELL BIOCHEMISTRY AND BIOPHYSICS,70(1),279-288. |
| MLA | Wang, Lin,et al."Adenosylmethionine Decarboxylase 1 (AMD1)-Mediated mRNA Processing and Cell Adhesion Activated & Inhibited Transition Mechanisms by Different Comparisons Between Chimpanzee and Human Left Hemisphere".CELL BIOCHEMISTRY AND BIOPHYSICS 70.1(2014):279-288. |
入库方式： OAI收割
来源：上海药物研究所
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