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Phragmalin-type limonoids with NF-kappa B inhibition from Chukrasia tabularis var. velutina

文献类型：期刊论文

作者Zhang, Feng1,2; Zhang, Chuan-Rui2; Tao, Xia1; Wang, Jun3; Chen, Wan-Sheng1; Yue, Jian-Min2
刊名BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
出版日期2014-08-15
卷号24期号:16页码:3791-3796
关键词Chukrasia tabularis var. velutina Phragmalin-type limonoids NF-kappa B inhibition
ISSN号0960-894X
DOI10.1016/j.bmcl.2014.06.069
文献子类Article
英文摘要Chemical investigation on Chukrasia tabularis var. velutina led to the identification of eight new phragmalin-type limonoids (1-8), as well as 20 known analogues. Compounds 1-4 are a rare class of C-15-acyl phragmalin-type limonoids, and particularly compounds 2-4 also possess a delta-lactone ring formed between C-16 and C-30. All the isolates were evaluated for inhibitory effects on NF-kappa B production, and four of which showed significant inhibitions. (C) 2014 Elsevier Ltd. All rights reserved.
WOS关键词A-D ; 16-NORPHRAGMALIN LIMONOIDS ; SKELETONS ; LEAVES ; TWIGS
资助项目Ministry of Science and Technology of the People's Republic of China[2012CB721105]
WOS研究方向Pharmacology & Pharmacy ; Chemistry
语种英语
WOS记录号WOS:000340565900023
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/276940]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Chen, Wan-Sheng
作者单位1.Second Mil Med Univ, Changzheng Hosp, Dept Pharm, Shanghai 200003, Peoples R China;
2.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China;
3.Second Mil Med Univ, Sch Pharm, Dept Pharmacol, Shanghai 200433, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Feng,Zhang, Chuan-Rui,Tao, Xia,et al. Phragmalin-type limonoids with NF-kappa B inhibition from Chukrasia tabularis var. velutina[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2014,24(16):3791-3796.
APA Zhang, Feng,Zhang, Chuan-Rui,Tao, Xia,Wang, Jun,Chen, Wan-Sheng,&Yue, Jian-Min.(2014).Phragmalin-type limonoids with NF-kappa B inhibition from Chukrasia tabularis var. velutina.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,24(16),3791-3796.
MLA Zhang, Feng,et al."Phragmalin-type limonoids with NF-kappa B inhibition from Chukrasia tabularis var. velutina".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 24.16(2014):3791-3796.

入库方式： OAI收割

来源：上海药物研究所

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