Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides
文献类型：期刊论文
| 作者 | Xu, Jing1,2; Jiang, Cheng-shi3; Zhang, Zai-long2; Ma, Wen-quan; Guo, Yue-wei3
|
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 2014-03 |
| 卷号 | 35期号:3页码:316-330 |
| 关键词 | natural product resorcinolic macrolide fungal metabolite bioactivity anti-tumor anti-bacteria anti-malaria biosynthesis |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2013.155 |
| 文献子类 | Review |
| 英文摘要 | Macrolides, which comprise a family of lactones with different ring sizes, belong to the polyketide class of natural products. Resorcinolic macrolides, an important subgroup, possess interesting structures and exhibit a wide variety of bioactivities, such as anti-tumor, anti-bacteria, and anti-malaria activities, etc. This review summarizes progress in isolation, bioactivity studies, biosynthesis, and representative chemical syntheses of this group of macrolides in recent decades, encompassing 63 naturally occurring macrolides published in 120 articles. |
| WOS关键词 | RESORCYLIC ACID LACTONES ; CURVULARIN-TYPE METABOLITES ; MODULAR ASYMMETRIC-SYNTHESIS ; POLYKETIDE SYNTHASE GENES ; RING-CLOSING-METATHESIS ; HEAT-SHOCK RESPONSE ; CITREO-VIRIDE-B ; GIBBERELLA-ZEAE ; AIGIALOMYCIN-D ; HSP90 INHIBITOR |
| 资助项目 | National Marine '863' Project[2011AA09070102] ; National Marine '863' Project[2013AA092902] ; National Natural Science Foundation of China[81302692] ; National Natural Science Foundation of China[81273430] ; National Natural Science Foundation of China[31070310] ; SKLDR/SIMM Project[SIMM1105KF-04] ; EU 7th Framework Programme-IRSES Project[246987] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| CSCD记录号 | CSCD:5067875 |
| WOS记录号 | WOS:000332467200002 |
| 出版者 | ACTA PHARMACOLOGICA SINICA |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277171]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Zhang, Zai-long |
| 作者单位 | 1.Weifang Biomed Innovat & Entrepreneurship Serv Ct, Weifang 261205, Peoples R China 2.China Univ Petr, Coll Sci, Qingdao 266580, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Xu, Jing,Jiang, Cheng-shi,Zhang, Zai-long,et al. Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides[J]. ACTA PHARMACOLOGICA SINICA,2014,35(3):316-330. |
| APA | Xu, Jing,Jiang, Cheng-shi,Zhang, Zai-long,Ma, Wen-quan,&Guo, Yue-wei.(2014).Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides.ACTA PHARMACOLOGICA SINICA,35(3),316-330. |
| MLA | Xu, Jing,et al."Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides".ACTA PHARMACOLOGICA SINICA 35.3(2014):316-330. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。