An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction
文献类型：期刊论文
| 作者 | Qian, Zhiwei; Yang, Anjiang; An, Weiteng; Yu, Ting; Wang, Xin ; Zhang, Yongliang; Shen, Jingkang; Meng, Tao
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2014 |
| 卷号 | 4期号:92页码:50947-50949 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c4ra09196e |
| 文献子类 | Article |
| 英文摘要 | A one-pot synthesis of 6-oxa-2,2a(1),11-triazadibenzo[cd,g]azulenes by a three-component reaction of a 2-aminoheterocycle, aldehydes, and 2-isocyanophenyl acetate is presented. This efficient and green protocol has the advantages of environmental friendliness, high yields and operational simplicity. The atropisomeric properties of this unique structure were examined by H-1 NMR spectroscopy and X-ray structural analyses, and the barriers to their interconversion were clarified. |
| WOS关键词 | 7-MEMBERED-RING BENZOLACTAMS ; ATROPISOMERIC PROPERTIES ; CONVERTIBLE ISONITRILES ; DERIVATIVES ; CONDENSATION ; CONFORMATION ; 3-COMPONENT ; NUCLEUS ; AGENTS |
| 资助项目 | National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2012ZX09103-101-026] ; National Natural Science Foundation of China[81473130] ; National Natural Science Foundation of China[81001355] ; National Natural Science Foundation of China[81273367] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000344325400081 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277261]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Shen, Jingkang |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qian, Zhiwei,Yang, Anjiang,An, Weiteng,et al. An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction[J]. RSC ADVANCES,2014,4(92):50947-50949. |
| APA | Qian, Zhiwei.,Yang, Anjiang.,An, Weiteng.,Yu, Ting.,Wang, Xin.,...&Meng, Tao.(2014).An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction.RSC ADVANCES,4(92),50947-50949. |
| MLA | Qian, Zhiwei,et al."An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction".RSC ADVANCES 4.92(2014):50947-50949. |
入库方式： OAI收割
来源：上海药物研究所
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