Catalyst-free synthesis of benzofuran-fused pyrido [4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions
文献类型：期刊论文
| 作者 | Li, Bo1,2; Yue, Zhizhou2; Xiang, Haoyue1; Lv, Linlin2; Song, Shanshan1; Miao, Zehong1; Yang, Chunhao1
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2014 |
| 卷号 | 4期号:1页码:358-364 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c3ra44828b |
| 文献子类 | Article |
| 英文摘要 | A rapid, one-pot, catalyst-free approach to novel benzofuran-fused pyrido[4,3-d]pyrimidines with good antitumor activities via a cascade SNAr/cyclization/condensation reaction through 2-(2-hydroxyphenyl) acetonitriles and 4,6-dichloropyrimidine-5-carbaldehyde was developed. |
| WOS关键词 | ALIPHATIC NITRILES SYNTHESIS ; ALKYL ARYL KETONES ; CASCADE REACTIONS ; TOPOISOMERASE-I ; INHIBITORS ; DERIVATIVES ; DISCOVERY ; POTENT ; ACID ; IDENTIFICATION |
| 资助项目 | "Interdisciplinary Cooperation Team" Program for Science and Technology Innovation of the Chinese Academy of Sciences[00000000] ; National Natural Science Foundation of China[21072205] ; National Natural Science Foundation of China[81025020] ; National Natural Science Foundation of China[SIMM1203ZZ-0103] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000327547000047 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277327]  |
| 专题 | 药理学第一研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物发现与设计中心 药物化学研究室 |
| 通讯作者 | Miao, Zehong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Wuhan Univ Technol, Sch Chem Engn, Dept Pharmaceut Engn, Wuhan 430070, Hubei, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Li, Bo,Yue, Zhizhou,Xiang, Haoyue,et al. Catalyst-free synthesis of benzofuran-fused pyrido [4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions[J]. RSC ADVANCES,2014,4(1):358-364. |
| APA | Li, Bo.,Yue, Zhizhou.,Xiang, Haoyue.,Lv, Linlin.,Song, Shanshan.,...&Yang, Chunhao.(2014).Catalyst-free synthesis of benzofuran-fused pyrido [4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions.RSC ADVANCES,4(1),358-364. |
| MLA | Li, Bo,et al."Catalyst-free synthesis of benzofuran-fused pyrido [4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions".RSC ADVANCES 4.1(2014):358-364. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。