DNA methylome: Unveiling your biological age
文献类型：期刊论文
| 作者 | Li, Ming2 ; Liu, Wensu2; Yuan, Tingting2; Bai, Ruijun2; Liu, Guang-Hui2,3,4; Zhang, Weizhou1; Qu, Jing2
|
| 刊名 | PROTEIN & CELL
 |
| 出版日期 | 2013-10 |
| 卷号 | 4期号:10页码:723-725 |
| ISSN号 | 1674-800X |
| DOI | 10.1007/s13238-013-3913-0 |
| 文献子类 | News Item |
| 英文摘要 | Hannum and colleagues performed DNA methylation sequencing to examine the relationship between DNA methylome and aging rate. Notably, they succeeded in building a quantitative and reproducible model based on the epigenetic bio-markers to predict aging rate with high accuracy. This progress enlightens us in many aspects particularly in applying this novel set of bio-markers on studying the mechanism of aging rate using adult tissue-specific stem cells, building up a potential quantitative model to explore the mechanism for other epigenetic factors like non-coding RNA, and understanding the principle and mechanism of 3D chromatin structure in epigenetic modulation. |
| WOS关键词 | STEM-CELLS ; TELOMERES ; IPSCS |
| 资助项目 | NCI NIH HHS[R00 CA158055] |
| WOS研究方向 | Cell Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000325432000001 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277440]  |
| 专题 | 新药研究国家重点实验室 中科院受体结构与功能重点实验室 |
| 通讯作者 | Liu, Guang-Hui |
| 作者单位 | 1.Univ Iowa, Dept Pathol, Carver Coll Med, Iowa City, IA 52242 USA 2.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 4.Beijing Inst Brain Disorders, Beijing 100069, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Li, Ming,Liu, Wensu,Yuan, Tingting,et al. DNA methylome: Unveiling your biological age[J]. PROTEIN & CELL,2013,4(10):723-725. |
| APA | Li, Ming.,Liu, Wensu.,Yuan, Tingting.,Bai, Ruijun.,Liu, Guang-Hui.,...&Qu, Jing.(2013).DNA methylome: Unveiling your biological age.PROTEIN & CELL,4(10),723-725. |
| MLA | Li, Ming,et al."DNA methylome: Unveiling your biological age".PROTEIN & CELL 4.10(2013):723-725. |
入库方式： OAI收割
来源：上海药物研究所
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