From monomer to tetramer and beyond: the intriguing chemistry of Securinega alkaloids from Flueggea virosa
文献类型：期刊论文
| 作者 | Zhang, Hua; Wei, Wei; Yue, Jian-Min
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2013-05-13 |
| 卷号 | 69期号:19页码:3942-3946 |
| 关键词 | Flueggea virosa Securinega alkaloid Alkaloid oligomer Flueggenine Fluevirosine Fluevirosinine |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2013.03.028 |
| 文献子类 | Article |
| 英文摘要 | A biosynthesis directed search for alkaloid oligomers from Flueggea virosa returned fluevirosinine A (4) as the first tetramer of the Securinega structure family, flueggenines C (1) and D (2) as two new dimers, and fluevirosine D (3) as a new trimer. Absolute structures were assigned to them on the basis of spectroscopic methods especially 2D NMR and CD data, as well as biogenetic considerations. The plausible biosynthetic route of these interesting oligomeric alkaloids was discussed, and some potential new analogues were also predicted from the currently available structures. (C) 2013 Elsevier Ltd. All rights reserved. |
| WOS关键词 | DIMERIC INDOLIZIDINE ALKALOIDS |
| 资助项目 | National Natural Science Foundation of P.R. China[21272244] ; Youth Innovation Promotion Association of Chinese Academy of Sciences[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000318137300025 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277619]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 期刊编辑部 新药研究国家重点实验室 分析化学研究室 |
| 通讯作者 | Yue, Jian-Min |
| 作者单位 | Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hua,Wei, Wei,Yue, Jian-Min. From monomer to tetramer and beyond: the intriguing chemistry of Securinega alkaloids from Flueggea virosa[J]. TETRAHEDRON,2013,69(19):3942-3946. |
| APA | Zhang, Hua,Wei, Wei,&Yue, Jian-Min.(2013).From monomer to tetramer and beyond: the intriguing chemistry of Securinega alkaloids from Flueggea virosa.TETRAHEDRON,69(19),3942-3946. |
| MLA | Zhang, Hua,et al."From monomer to tetramer and beyond: the intriguing chemistry of Securinega alkaloids from Flueggea virosa".TETRAHEDRON 69.19(2013):3942-3946. |
入库方式： OAI收割
来源：上海药物研究所
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