Polyoxygenated diterpenoids of the eunicellin-type from the Chinese soft coral Cladiella krempfi
文献类型：期刊论文
| 作者 | Cai, You-Sheng4; Yao, Li-Gong4; Di Pascale, Antonio2; Irace, Carlo2; Mollo, Ernesto1; Taglialatela-Scafati, Orazio3; Guo, Yue-Wei4
|
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2013-03-04 |
| 卷号 | 69期号:9页码:2214-2219 |
| 关键词 | Cladiella krempfi Diterpenoids Eunicellin Structure elucidation Bioactivity |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2012.12.051 |
| 文献子类 | Article |
| 英文摘要 | A detailed chemical investigation of the Chinese soft coral Cladiella krempfi has yielded four new eunicellin-based diterpenoids along with five known compounds. The stereostructures of the new metabolites have been elucidated by extensive spectroscopic analysis, mainly based on 2D NMR spectroscopy, and by chemical transformations. A remarkable variation in the diterpene composition in dependence of the exact site of collection was observed. Some of the isolated diterpenoids were shown to exhibit antiproliferative activity against C6 glioma cells, multi-drug resistant tumor cell line. (c) 2012 Elsevier Ltd. All rights reserved. |
| WOS关键词 | SINULARIA-FLEXIBILIS ; LITOPHYTON SP ; A-D ; SCLEROPHYTIN ; OCTOCORALLIA |
| 资助项目 | Natural Science Foundation of China[21072204] ; Natural Science Foundation of China[81273430] ; Natural Science Foundation of China[21021063] ; National Marine '863' Project[2011AA09070102] ; National Marine '863' Project[2013AA092902] ; SKLDR/SIMM Projects[SIMM1203ZZ-03] ; EU 7th Framework Programme-IRSES Project[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000315062900018 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277700]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Taglialatela-Scafati, Orazio |
| 作者单位 | 1.Ist Chim Biomol ICB CNR, I-80078 Naples, Italy; 2.Univ Naples Federico II, Dipartimento Farmacol Sperimentale, I-80131 Naples, Italy; 3.Univ Naples Federico II, Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200031, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Cai, You-Sheng,Yao, Li-Gong,Di Pascale, Antonio,et al. Polyoxygenated diterpenoids of the eunicellin-type from the Chinese soft coral Cladiella krempfi[J]. TETRAHEDRON,2013,69(9):2214-2219. |
| APA | Cai, You-Sheng.,Yao, Li-Gong.,Di Pascale, Antonio.,Irace, Carlo.,Mollo, Ernesto.,...&Guo, Yue-Wei.(2013).Polyoxygenated diterpenoids of the eunicellin-type from the Chinese soft coral Cladiella krempfi.TETRAHEDRON,69(9),2214-2219. |
| MLA | Cai, You-Sheng,et al."Polyoxygenated diterpenoids of the eunicellin-type from the Chinese soft coral Cladiella krempfi".TETRAHEDRON 69.9(2013):2214-2219. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。