Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes
文献类型：期刊论文
| 作者 | Ding, Xiao3; Wang, Hengshuai3; Wang, Jiang3 ; Wang, Sinan3; Lin, Daizong3; Lv, Li3; Zhou, Yu3; Luo, Xiaomin3; Jiang, Hualiang3; Luis Acena, Jose2
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| 刊名 | AMINO ACIDS
 |
| 出版日期 | 2013-02 |
| 卷号 | 44期号:2页码:791-796 |
| 关键词 | Diels-Alder reaction Nickel (II) beta-Alanine beta-Aminocyclohexane carboxylic acids |
| ISSN号 | 0939-4451 |
| DOI | 10.1007/s00726-012-1404-x |
| 文献子类 | Article |
| 英文摘要 | This paper describes the design and synthesis of a new class of beta-alanine derived dienes stabilized by Ni(II)-complex. Preliminary study of their Diels-Alder cycloaddition reactions with several types of dienophiles demonstrates their significant synthetic potential for the preparation of various polyfunctional beta-aminocyclohexane carboxylic acids. |
| WOS关键词 | MICHAEL ADDITION-REACTIONS ; NUCLEOPHILIC GLYCINE EQUIVALENTS ; EFFICIENT ASYMMETRIC-SYNTHESIS ; SUBSTITUTED PYROGLUTAMIC ACIDS ; VIRTUALLY COMPLETE CONTROL ; CHIRAL NI(II) COMPLEX ; LARGE-SCALE SYNTHESIS ; ALPHA-AMINO ; ALDOL REACTIONS ; FACE DIASTEREOSELECTIVITY |
| 资助项目 | National Basic Research Program of China[2009CB940903] ; National Basic Research Program of China[2009CB918502] ; National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[81025017] ; National S&T Major Projects[2012ZX09103-101-072] ; China-EU Science and Technology Cooperation Project[1109] ; Silver Project[260644] |
| WOS研究方向 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000313794600046 |
| 出版者 | SPRINGER WIEN |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277747]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物发现与设计中心 |
| 通讯作者 | Liu, Hong |
| 作者单位 | 1.Univ Basque Country UPV EHU, San Sebastian, Spain 2.Basque Fdn Sci, IKERBASQUE, Bilbao 48011, Spain; 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Ding, Xiao,Wang, Hengshuai,Wang, Jiang,et al. Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes[J]. AMINO ACIDS,2013,44(2):791-796. |
| APA | Ding, Xiao.,Wang, Hengshuai.,Wang, Jiang.,Wang, Sinan.,Lin, Daizong.,...&Liu, Hong.(2013).Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes.AMINO ACIDS,44(2),791-796. |
| MLA | Ding, Xiao,et al."Synthesis of polysubstituted beta-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized beta-alanine derived dienes".AMINO ACIDS 44.2(2013):791-796. |
入库方式： OAI收割
来源：上海药物研究所
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