A novel convenient approach towards pyrrolo[1,2-b]-pyridazines through a domino coupling-isomerization-condensation reaction
文献类型：期刊论文
| 作者 | Wang, Meng; Tan, Cun; He, Qian ; Xie, Yuyuan; Yang, Chunhao
|
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 11期号:16页码:2574-2577 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c3ob40157j |
| 文献子类 | Article |
| 英文摘要 | A novel Pd/Cu catalyzed domino reaction for the synthesis of functionalized pyrrolo[1,2-b]pyridazines from readily accessible ( hetero)aryl propargyl alcohols and 1-amino-2-bromopyrroles was developed. This cascade process involves a Sonogashira cross-coupling reaction, an isomerization and an intramolecular condensation. |
| WOS关键词 | FLUORESCENT PYRROLOPYRIDAZINE DERIVATIVES ; BLUE ORGANIC LUMINOPHORS ; HIGHLY FLUORESCENT ; REACTION MACIR ; INHIBITORS ; SEQUENCE ; 1,2-DIAZINES ; ANTAGONISTS ; PYRIDAZINE ; QUINOLINES |
| 资助项目 | Ministry of Science and Technology of China ("Key New Drug Creation and Manufacturing Program")[2012ZX09301001-001] ; Ministry of Science and Technology of China ("Key New Drug Creation and Manufacturing Program")[2012ZX09103101-071] ; Chinese Academy of Sciences ("Interdisciplinary Cooperation Team" Program for Science and Technology Innovation)[00000000] ; National Natural Science Foundation of China (NSFC)[21072205] ; SKLDR/SIMM[SIMM1203ZZ-0103] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000316803900004 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277797]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yang, Chunhao |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Meng,Tan, Cun,He, Qian,et al. A novel convenient approach towards pyrrolo[1,2-b]-pyridazines through a domino coupling-isomerization-condensation reaction[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2013,11(16):2574-2577. |
| APA | Wang, Meng,Tan, Cun,He, Qian,Xie, Yuyuan,&Yang, Chunhao.(2013).A novel convenient approach towards pyrrolo[1,2-b]-pyridazines through a domino coupling-isomerization-condensation reaction.ORGANIC & BIOMOLECULAR CHEMISTRY,11(16),2574-2577. |
| MLA | Wang, Meng,et al."A novel convenient approach towards pyrrolo[1,2-b]-pyridazines through a domino coupling-isomerization-condensation reaction".ORGANIC & BIOMOLECULAR CHEMISTRY 11.16(2013):2574-2577. |
入库方式： OAI收割
来源：上海药物研究所
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