Palladium(II)-catalyzed synthesis of functionalized indenones via oxidation and cyclization of 2-(2-arylethynylphenyl)acetonitriles
文献类型：期刊论文
| 作者 | Chen, Xuxing; He, Qian ; Xie, Yuyuan; Yang, Chunhao
|
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 11期号:16页码:2582-2585 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c3ob40103k |
| 文献子类 | Article |
| 英文摘要 | A one-pot two-step synthesis of versatile indenones has been developed. This palladium(II)-catalyzed transformation involves generation and condensation of ortho-functionalized 1,2-benzils from 2-(2-arylethynylphenyl)acetonitriles using Ph2SO as the oxidant. The resulting 3-cyanoindenones can be converted to various valuable molecules. |
| WOS关键词 | UNSYMMETRICAL NONSTEROIDAL LIGANDS ; C-H BOND ; ESTROGEN-RECEPTOR ; CATALYZED ANNULATION ; BINDING ORIENTATION ; ANTICANCER AGENTS ; INTERNAL ALKYNES ; INHIBITORS ; DMSO ; 2-ARYLINDENONES |
| 资助项目 | "Interdisciplinary Cooperation Team" Program for Science and Technology Innovation of the Chinese Academy of Sciences[00000000] ; National Natural Science Foundation of China[21072205] ; National Natural Science Foundation of China[SIMM1203ZZ-0103] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000316803900006 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277798]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yang, Chunhao |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Xuxing,He, Qian,Xie, Yuyuan,et al. Palladium(II)-catalyzed synthesis of functionalized indenones via oxidation and cyclization of 2-(2-arylethynylphenyl)acetonitriles[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2013,11(16):2582-2585. |
| APA | Chen, Xuxing,He, Qian,Xie, Yuyuan,&Yang, Chunhao.(2013).Palladium(II)-catalyzed synthesis of functionalized indenones via oxidation and cyclization of 2-(2-arylethynylphenyl)acetonitriles.ORGANIC & BIOMOLECULAR CHEMISTRY,11(16),2582-2585. |
| MLA | Chen, Xuxing,et al."Palladium(II)-catalyzed synthesis of functionalized indenones via oxidation and cyclization of 2-(2-arylethynylphenyl)acetonitriles".ORGANIC & BIOMOLECULAR CHEMISTRY 11.16(2013):2582-2585. |
入库方式： OAI收割
来源：上海药物研究所
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